SEPT11

Septin-11 is a protein that in humans is encoded by the SEPT11 gene.[5][6][7]

SEPTIN11
Identifiers
Aliases	SEPTIN11, septin 11, SEPT11
External IDs	OMIM: 612887 MGI: 1277214 HomoloGene: 56800 GeneCards: SEPTIN11
Gene location (Human) Chr. Chromosome 4 (human)[1] Band 4q21.1 Start 76,949,703 bp[1] End 77,040,384 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5 E2|5 47.29 cM Start 93,093,437 bp[2] End 93,176,447 bp[2]
Gene ontology Molecular function • nucleotide binding • GTP binding • GO:0001948 protein binding • GTPase activity • GO:0032947 molecular adaptor activity Cellular component • cytoplasm • axon • cell junction • dendritic spine • cell projection • synapse • cytoskeleton • stress fiber • postsynapse • glutamatergic synapse • GABA-ergic synapse • postsynaptic specialization of symmetric synapse • septin ring • microtubule cytoskeleton • septin complex • septin filament array Biological process • cell cycle • protein heterooligomerization • cell division • regulation of synapse organization • mitotic cytokinesis • septin ring assembly • cilium morphogenesis • cytoskeleton-dependent cytokinesis Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	55752	52398
Ensembl	ENSG00000138758	ENSMUSG00000058013
UniProt	Q9NVA2	Q8C1B7
RefSeq (mRNA)	NM_001306147 NM_018243	NM_001009818 NM_001310669 NM_001310671 NM_001347377
RefSeq (protein)	NP_001293076 NP_060713	NP_001009818 NP_001297598 NP_001297600 NP_001334306
Location (UCSC)	Chr 4: 76.95 – 77.04 Mb	Chr 5: 93.09 – 93.18 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000138758 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000058013 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Kojima K, Sakai I, Hasegawa A, Niiya H, Azuma T, Matsuo Y, Fujii N, Tanimoto M, Fujita S (May 2004). "FLJ10849, a septin family gene, fuses MLL in a novel leukemia cell line CNLBC1 derived from chronic neutrophilic leukemia in transformation with t(4;11)(q21;q23)". Leukemia. 18 (5): 998–1005. doi:10.1038/sj.leu.2403334. PMID 14999297.
6. Kim DS, Hubbard SL, Peraud A, Salhia B, Sakai K, Rutka JT (May 2004). "Analysis of mammalian septin expression in human malignant brain tumors". Neoplasia. 6 (2): 168–78. doi:10.1593/neo.03310. PMC 1502092. PMID 15140406.
7. "Entrez Gene: SEPT11 septin 11".

Further reading

• Andersen JS, Lyon CE, Fox AH, Leung AK, Lam YW, Steen H, Mann M, Lamond AI (January 2002). "Directed proteomic analysis of the human nucleolus". Current Biology. 12 (1): 1–11. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298.
• Wistow G, Bernstein SL, Wyatt MK, Fariss RN, Behal A, Touchman JW, Bouffard G, Smith D, Peterson K (June 2002). "Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes and splice variants". Molecular Vision. 8: 205–20. PMID 12107410.
• Gevaert K, Goethals M, Martens L, Van Damme J, Staes A, Thomas GR, Vandekerckhove J (May 2003). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides". Nature Biotechnology. 21 (5): 566–9. doi:10.1038/nbt810. PMID 12665801.
• Hanai N, Nagata K, Kawajiri A, Shiromizu T, Saitoh N, Hasegawa Y, Murakami S, Inagaki M (June 2004). "Biochemical and cell biological characterization of a mammalian septin, Sept11". FEBS Letters. 568 (1–3): 83–8. doi:10.1016/j.febslet.2004.05.030. PMID 15196925.
• Nagata K, Asano T, Nozawa Y, Inagaki M (December 2004). "Biochemical and cell biological analyses of a mammalian septin complex, Sept7/9b/11". The Journal of Biological Chemistry. 279 (53): 55895–904. doi:10.1074/jbc.M406153200. PMID 15485874.
• Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M (January 2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. doi:10.1038/nature03207. PMID 15635413.
• Sudo K, Ito H, Iwamoto I, Morishita R, Asano T, Nagata K (October 2007). "SEPT9 sequence alternations causing hereditary neuralgic amyotrophy are associated with altered interactions with SEPT4/SEPT11 and resistance to Rho/Rhotekin-signaling". Human Mutation. 28 (10): 1005–13. doi:10.1002/humu.20554. PMID 17546647.
• Xin X, Pache M, Zieger B, Bartsch I, Prünte C, Flammer J, Meyer P (November 2007). "Septin expression in proliferative retinal membranes". The Journal of Histochemistry and Cytochemistry. 55 (11): 1089–94. doi:10.1369/jhc.7A7188.2007. PMC 3957527. PMID 17625225.