SDF4

45 kDa calcium-binding protein is a protein that in humans is encoded by the SDF4 gene.[5][6][7]

SDF4
Identifiers
Aliases	SDF4, Cab45, SDF-4, stromal cell derived factor 4
External IDs	OMIM: 614282 MGI: 108079 HomoloGene: 32121 GeneCards: SDF4
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p36.33 Start 1,216,908 bp[1] End 1,232,067 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4|4 E2 Start 155,992,872 bp[2] End 156,013,610 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001948 protein binding • metal ion binding • identical protein binding • calcium ion binding Cellular component • cell projection • extracellular exosome • bleb • late endosome • Golgi lumen • cytoplasm • membrane • cell membrane • Golgi apparatus • endoplasmic reticulum Biological process • UV protection • zymogen granule exocytosis • response to ethanol • cerebellum development • calcium ion regulated exocytosis • exocytosis • fat cell differentiation Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	51150	20318
Ensembl	ENSG00000078808	ENSMUSG00000029076
UniProt	Q9BRK5	Q61112
RefSeq (mRNA)	NM_016176 NM_016547	NM_011341 NM_001302467 NM_001302468 NM_001302469
RefSeq (protein)	NP_057260 NP_057631	NP_001289396 NP_001289397 NP_001289398 NP_035471
Location (UCSC)	Chr 1: 1.22 – 1.23 Mb	Chr 4: 155.99 – 156.01 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000078808 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000029076 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Koivu T, Laitinen S, Riento K, Olkkonen VM (Sep 1997). "Sequence of a human cDNA encoding Cab45, a Ca2+-binding protein with six EF-hand motifs". DNA Seq. 7 (3–4): 217–20. doi:10.3109/10425179709034038. PMID 9254016.
6. Scherer PE, Lederkremer GZ, Williams S, Fogliano M, Baldini G, Lodish HF (May 1996). "Cab45, a novel (Ca2+)-binding protein localized to the Golgi lumen". J Cell Biol. 133 (2): 257–68. doi:10.1083/jcb.133.2.257. PMC 2120788. PMID 8609160.
7. "Entrez Gene: SDF4 stromal cell derived factor 4".

Further reading

• Honoré B, Vorum H (2000). "The CREC family, a novel family of multiple EF-hand, low-affinity Ca(2+)-binding proteins localised to the secretory pathway of mammalian cells". FEBS Lett. 466 (1): 11–8. doi:10.1016/S0014-5793(99)01780-9. PMID 10648803.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
• Lam PP, Hyvärinen K, Kauppi M, et al. (2007). "A cytosolic splice variant of Cab45 interacts with Munc18b and impacts on amylase secretion by pancreatic acini". Mol. Biol. Cell. 18 (7): 2473–80. doi:10.1091/mbc.E06-10-0950. PMC 1924827. PMID 17442889.