Syntenin-2

Syntenin-2 is a protein that in humans is encoded by the SDCBP2 gene.[5][6]

SDCBP2
Identifiers
Aliases	SDCBP2, SITAC, SITAC18, ST-2, syndecan binding protein 2, ST2
External IDs	OMIM: 617358 MGI: 2385156 HomoloGene: 9240 GeneCards: SDCBP2
Gene location (Human) Chr. Chromosome 20 (human)[1] Band 20p13 Start 1,309,909 bp[1] End 1,329,139 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 G3 Start 151,572,622 bp[2] End 151,590,005 bp[2]
Gene ontology Molecular function • protein C-terminus binding • GO:0001948 protein binding • protein homodimerization activity • protein heterodimerization activity • identical protein binding • phosphatidylinositol-4,5-bisphosphate binding • lipid binding Cellular component • extracellular exosome • cell nucleus • nucleoplasm • nucleolus • cytoplasm • cell membrane • membrane • nuclear speck Biological process • GO:0007243 intracellular signal transduction • intracellular transport • nervous system development • cellular proliferation Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	27111	228765
Ensembl	ENSG00000125775	ENSMUSG00000027456
UniProt	Q9H190	Q99JZ0
RefSeq (mRNA)	NM_080489 NM_001199784 NM_015685	NM_145535
RefSeq (protein)	NP_001186713 NP_056500 NP_536737	NP_663510
Location (UCSC)	Chr 20: 1.31 – 1.33 Mb	Chr 2: 151.57 – 151.59 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000125775 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000027456 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Koroll M, Rathjen FG, Volkmer H (Apr 2001). "The neural cell recognition molecule neurofascin interacts with syntenin-1 but not with syntenin-2, both of which reveal self-associating activity". J Biol Chem. 276 (14): 10646–54. doi:10.1074/jbc.M010647200. PMID 11152476.
6. "Entrez Gene: SDCBP2 syndecan binding protein (syntenin) 2".

Further reading

• Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
• Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
• Borrell-Pagès M, Fernández-Larrea J, Borroto A, et al. (2001). "The carboxy-terminal cysteine of the tetraspanin L6 antigen is required for its interaction with SITAC, a novel PDZ protein". Mol. Biol. Cell. 11 (12): 4217–25. doi:10.1091/mbc.11.12.4217. PMC 15068. PMID 11102519.
• Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. doi:10.1038/414865a. PMID 11780052.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.