SCYL3

Protein-associating with the carboxyl-terminal domain of ezrin is a protein that in humans is encoded by the SCYL3 gene.[5][6]

SCYL3
Identifiers
Aliases	SCYL3, PACE-1, PACE1, SCY1 like pseudokinase 3
External IDs	OMIM: 608192 MGI: 1921385 HomoloGene: 10706 GeneCards: SCYL3
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q24.2 Start 169,849,631 bp[1] End 169,894,267 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1|1 H2.1 Start 163,929,100 bp[2] End 163,955,126 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001948 protein binding • ATP binding • kinase activity Cellular component • cytoplasm • Golgi apparatus • cell projection • lamellipodium Biological process • protein phosphorylation • cell migration Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	57147	240880
Ensembl	ENSG00000000457	ENSMUSG00000026584
UniProt	Q8IZE3	Q9DBQ7
RefSeq (mRNA)	NM_020423 NM_181093	NM_001286002 NM_001286003 NM_028776 NM_001357426
RefSeq (protein)	NP_065156 NP_851607	NP_001272931 NP_001272932 NP_083052 NP_001344355
Location (UCSC)	Chr 1: 169.85 – 169.89 Mb	Chr 1: 163.93 – 163.96 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000000457 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000026584 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Sullivan A, Uff CR, Isacke CM, Thorne RF (Mar 2003). "PACE-1, a novel protein that interacts with the C-terminal domain of ezrin". Exp Cell Res. 284 (2): 224–38. doi:10.1016/S0014-4827(02)00054-X. PMID 12651155.
6. "Entrez Gene: SCYL3 SCY1-like 3 (S. cerevisiae)".

Further reading

• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Maurer-Stroh S, Gouda M, Novatchkova M, et al. (2004). "MYRbase: analysis of genome-wide glycine myristoylation enlarges the functional spectrum of eukaryotic myristoylated proteins". Genome Biol. 5 (3): R21. doi:10.1186/gb-2004-5-3-r21. PMC 395771. PMID 15003124.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.