SAMD4B

Sterile alpha motif domain containing 4B is a protein that in humans is encoded by the SAMD4B gene. [5]

SAMD4B
Identifiers
Aliases	SAMD4B, SMGB, hSmaug2, Smaug2, sterile alpha motif domain containing 4B
External IDs	MGI: 2448542 HomoloGene: 35268 GeneCards: SAMD4B
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19q13.2 Start 39,342,396 bp[1] End 39,385,710 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 B1 Start 28,399,522 bp[2] End 28,598,144 bp[2]
Gene ontology Molecular function • mRNA binding • translation repressor activity • RNA binding Cellular component • cell nucleus • P-body • cytoplasm • cytosol Biological process • regulation of transcription, DNA-templated • transcription, DNA-templated • nuclear-transcribed mRNA poly(A) tail shortening • regulation of mRNA stability • negative regulation of translation Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	55095	233033
Ensembl	ENSG00000179134	ENSMUSG00000109336
UniProt	Q5PRF9	Q80XS6
RefSeq (mRNA)	NM_001303614 NM_018028	NM_175021
RefSeq (protein)	NP_001290543 NP_060498	n/a
Location (UCSC)	Chr 19: 39.34 – 39.39 Mb	Chr 7: 28.4 – 28.6 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000179134 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000109336 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Sterile alpha motif domain containing 4B". Retrieved 2020-04-16.

Further reading

• Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD (November 2009). "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip". Am. J. Hum. Genet. 85 (5): 628–42. doi:10.1016/j.ajhg.2009.10.014. PMC 2775832. PMID 19913121.
• Luo N, Li G, Li Y, Fan X, Wang Y, Ye X, Mo X, Zhou J, Yuan W, Tan M, Xie H, Ocorr K, Bodmer R, Deng Y, Wu X (May 2010). "SAMD4B, a novel SAM-containing protein, inhibits AP-1-, p53- and p21-mediated transcriptional activity". BMB Rep. 43 (5): 355–61. doi:10.5483/bmbrep.2010.43.5.355. PMID 20510020.