RBP7

Retinol binding protein 7 is a protein that in humans is encoded by the RBP7 gene. [5]

RBP7
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1LPJ
Identifiers
Aliases	RBP7, CRBP4, CRBPIV, retinol binding protein 7, CRABP4
External IDs	OMIM: 608604 MGI: 1890409 HomoloGene: 32521 GeneCards: RBP7
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p36.22 Start 9,997,206 bp[1] End 10,016,021 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4|4 E2 Start 149,449,687 bp[2] End 149,454,978 bp[2]
Gene ontology Molecular function • retinol binding • GO:0001948 protein binding • retinoid binding • retinal binding • lipid binding Cellular component • cytoplasm Biological process • transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	116362	63954
Ensembl	ENSG00000162444	ENSMUSG00000028996
UniProt	Q96R05	Q9EPC5
RefSeq (mRNA)	NM_052960	NM_022020
RefSeq (protein)	NP_443192	NP_071303
Location (UCSC)	Chr 1: 10 – 10.02 Mb	Chr 4: 149.45 – 149.45 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Function

The protein encoded by this gene is a member of the cellular retinol-binding protein (CRBP) family, whose members are required for vitamin A stability and metabolism. The encoded protein binds all-trans-retinol and is structurally similar to other CRBPs; however, it has a lower binding affinity for retinol than other CRBPs. [provided by RefSeq, Aug 2016].

References

1. GRCh38: Ensembl release 89: ENSG00000162444 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000028996 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Retinol binding protein 7". Retrieved 2018-01-11.

External links

• PDBe-KB provides an overview of all the structure information available in the PDB for Human Retinoid-binding protein 7

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.