Protein BEX1

Protein BEX1 also known as brain-expressed X-linked protein 1 is a protein that in humans is encoded by the BEX1 gene.[5]

BEX1
Identifiers
Aliases	BEX1, BEX2, HBEX2, HGR74-h, brain expressed X-linked 1
External IDs	OMIM: 300690 MGI: 1338017 HomoloGene: 135613 GeneCards: BEX1
Gene location (Human) Chr. X chromosome (human)[1] Band Xq22.1|Xq22 Start 103,062,651 bp[1] End 103,064,171 bp[1]
Gene location (Mouse) Chr. X chromosome (mouse)[2] Band X F1|X 57.37 cM Start 136,066,564 bp[2] End 136,068,236 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • RNA polymerase II activating transcription factor binding • GO:0001948 protein binding Cellular component • cytoplasm • cell nucleus • transcription factor complex Biological process • multicellular organism development • cell differentiation • positive regulation of sequence-specific DNA binding transcription factor activity • nervous system development • positive regulation of transcription from RNA polymerase II promoter Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	55859	12069
Ensembl	ENSG00000133169	ENSMUSG00000042750
UniProt	Q9HBH7	Q9WTZ8
RefSeq (mRNA)	NM_018476	NM_009749
RefSeq (protein)	NP_060946	NP_033879
Location (UCSC)	Chr X: 103.06 – 103.06 Mb	Chr X: 136.07 – 136.07 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000133169 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000042750 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: BEX1 brain expressed, X-linked 1".

Further reading

• Foltz G, Ryu GY, Yoon JG, et al. (2006). "Genome-wide analysis of epigenetic silencing identifies BEX1 and BEX2 as candidate tumor suppressor genes in malignant glioma". Cancer Res. 66 (13): 6665–74. doi:10.1158/0008-5472.CAN-05-4453. PMID 16818640.
• Alvarez E, Zhou W, Witta SE, Freed CR (2005). "Characterization of the Bex gene family in humans, mice, and rats". Gene. 357 (1): 18–28. doi:10.1016/j.gene.2005.05.012. PMID 15958283.
• Quentmeier H, Tonelli R, Geffers R, et al. (2005). "Expression of BEX1 in acute myeloid leukemia with MLL rearrangements". Leukemia. 19 (8): 1488–9. doi:10.1038/sj.leu.2403820. PMID 15920485.
• Baldisseri DM, Margolis JW, Weber DJ, et al. (2002). "Olfactory marker protein (OMP) exhibits a beta-clam fold in solution: implications for target peptide interaction and olfactory signal transduction". J. Mol. Biol. 319 (3): 823–37. doi:10.1016/S0022-2836(02)00282-6. PMID 12054873.
• Yang QS, Xia F, Gu SH, et al. (2002). "Cloning and expression pattern of a spermatogenesis-related gene, BEX1, mapped to chromosome Xq22". Biochem. Genet. 40 (1–2): 1–12. doi:10.1023/A:1014565320998. PMID 11989783.