Propagermanium

Propagermanium
Names
	IUPAC name 3-[(2-Carboxyethyl-oxogermyl)oxy-oxogermyl]propanoic acid
	Other names proxigermanium, Ge-132, germanium sesquioxide, 2-carboxyethylgermasesquioxane, SK-818, bis(2-carboxyethylgermanium) sesquioxide
Identifiers
CAS Number	12758-40-6 ;
3D model (JSmol)	Interactive image;
ECHA InfoCard	100.032.533
PubChem CID	83030;
UNII	1Q2P9TO9Q7 ;
CompTox Dashboard (EPA)	DTXSID9065316 ;
	SMILES C(C[Ge](=O)O[Ge](=O)CCC(=O)O)C(=O)O;
Properties
Chemical formula	C6H10O7Ge2
Molar mass	339.4222 g/mol
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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	Infobox references

Propagermanium (INN), also known by a variety of other names including bis(2-carboxyethylgermanium) sesquioxide and 2-carboxyethylgermasesquioxane, is an organometallic compound of germanium[1] that is sold as an alternative medicine. It is a polymeric compound with the formula ((HOOCCH₂CH₂Ge)₂O₃)_n.

The compound was first synthesized in 1967 at the Asai Germanium Research Institute in Japan. It is a water-soluble organogermanium compound used as raw material in health foods. The compound displays low toxicity in studies with rats. [2]

References

M.P. Egorov, P.P. Gaspar (1994), Germanium: Organometallic chemistry in Encyclopedia of Inorganic Chemistry. John Wiley & Sons ISBN 0-471-93620-0
Doi, Yuko; et al. (2017). "No carcinogenicity of poly-trans-[(2-carboxyethyl) germasesquioxane] (Ge-132): 26-week feeding study using rasH2 mice". Fundamental Toxicological Sciences. 4 (3): 137–150. doi:10.2131/fts.4.137.

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[1] M.P. Egorov, P.P. Gaspar (1994), Germanium: Organometallic chemistry in Encyclopedia of Inorganic Chemistry. John Wiley & Sons ISBN 0-471-93620-0

[2] Doi, Yuko; et al. (2017). "No carcinogenicity of poly-trans-[(2-carboxyethyl) germasesquioxane] (Ge-132): 26-week feeding study using rasH2 mice". Fundamental Toxicological Sciences. 4 (3): 137–150. doi:10.2131/fts.4.137.