Platypnea-orthodeoxia syndrome
Platypnea–orthodeoxia syndrome is a condition in which a person has shortness of breath and low oxygen saturations when upright (platypnea and orthodeoxia), but no symptoms when lying down. It can be caused by ventilation-perfusion mismatch, intracardiac shunting, or pulmonary shunting. In some cases, the cause is multifactorial.[1][2]
| Platypnea-orthodeoxia syndrome | |
|---|---|
| Differential diagnosis | intracardiac shunting |
References
- Henkin, Stanislav; Negrotto, Sara; Pollak, Peter M.; Cullen, Michael W.; O'Cochlain, D. Fearghas; Wright, R. Scott (2015-10-01). "Platypnea-Orthodeoxia Syndrome: Diagnostic Challenge and the Importance of Heightened Clinical Suspicion". Texas Heart Institute Journal. 42 (5): 498–501. doi:10.14503/THIJ-14-4596. ISSN 0730-2347. PMC 4591898. PMID 26504452.
- De Vecchis, Renato; Baldi, Cesare; Ariano, Carmelina (2016-09-23). "Platypnea–Orthodeoxia Syndrome: Multiple Pathophysiological Interpretations of a Clinical Picture Primarily Consisting of Orthostatic Dyspnea". Journal of Clinical Medicine. 5 (10): 85. doi:10.3390/jcm5100085. ISSN 2077-0383. PMC 5086587. PMID 27669319.
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