Phosphatidylinositol transfer protein, alpha

PITPNA
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1UW5
Identifiers
Aliases	PITPNA, HEL-S-36, PI-TPalpha, PITPN, VIB1A, phosphatidylinositol transfer protein alpha
External IDs	OMIM: 600174 MGI: 99887 HomoloGene: 55958 GeneCards: PITPNA
Gene location (Human)
Chr.	Chromosome 17 (human)[1]
End	1,562,792 bp[1]
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)[2]
End	75,628,804 bp[2]
RNA expression pattern
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	• lipid binding; • phosphatidylcholine transporter activity; • phosphatidylinositol transporter activity; • phosphatidylcholine binding; • phosphatidylinositol binding; • phosphatidylglycerol binding; • phospholipid transporter activity;
Cellular component	• cytoplasm; • myelin; • extracellular exosome; • intracellular; • cytosol;
Biological process	• visual perception; • lipid metabolism; • axonogenesis; • phospholipid transport; • interleukin-12-mediated signaling pathway; • transport;
	Sources:Amigo / QuickGO
Orthologs
	5306
	18738
	ENSG00000174238
	ENSMUSG00000017781
	Q00169
	P53810
	NM_006224
	NM_008850
	NP_006215
	NP_032876
	Wikidata
View/Edit Human	View/Edit Mouse

Phosphatidylinositol transfer protein alpha isoform is a protein that in humans is encoded by the PITPNA gene.[5]

Phosphatidylinositol transfer proteins are a diverse set of cytosolic phospholipid transfer proteins that are distinguished by their ability to transfer phospholipids between membranes in vitro (Wirtz, 1991).[6]

References

GRCh38: Ensembl release 89: ENSG00000174238 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000017781 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Hay JC, Martin TF (Jan 1994). "Phosphatidylinositol transfer protein required for ATP-dependent priming of Ca(2+)-activated secretion". Nature. 366 (6455): 572–5. doi:10.1038/366572a0. PMID 8255295.
"Entrez Gene: PITPNA phosphatidylinositol transfer protein, alpha".