Phonophoresis

Phonophoresis is the use of ultrasound to enhance the delivery of topically applied drugs.[1][2] Phonophoresis has been used in an effort to enhance the absorption of topically applied analgesics and anti-inflammatory agents through the therapeutic application of ultrasound.

Phonophoresis procedure

Phonophoresis has been shown to be ineffective for some treatments[3], where it did not increase the efficacy of absorption of drugs, or did not improve the outcome more than the use of ultrasound alone.[4][5]

See also

• Iontophoresis

References

1. Skauen, Donald M.; Zentner, Gaylen M. (1984). "Phonophoresis". International Journal of Pharmaceutics. 20 (3): 235–245. doi:10.1016/0378-5173(84)90171-6. ISSN 0378-5173.
2. Tyle, Praveen; Agrawala, Praful (1989). "Drug Delivery by Phonophoresis". Pharmaceutical Research. 06 (5): 355–361. doi:10.1023/A:1015967012253. ISSN 0724-8741.
3. https://journals.lww.com/clinicalpain/Citation/2013/10000/Phonophoresis_Versus_Placebo_for_Carpal_Tunnel.12.aspx
4. Klaiman, Mark D.; Shrader, Joseph A.; Danoff, Jerome V.; Hicks, Jeanne E.; Pesce, William J.; Ferland, James (1998). "Phonophoresis versus ultrasound in the treatment of common musculoskeletal conditions". Medicine & Science in Sports & Exercise. 30 (9): 1349–1355. doi:10.1097/00005768-199809000-00002. ISSN 0195-9131.
5. Ay, Saime; Doğan, Şebnem Koldaş; Evcik, Deniz; Başer, Özgün Çakmak (2010). "Comparison the efficacy of phonophoresis and ultrasound therapy in myofascial pain syndrome". Rheumatology International. 31 (9): 1203–1208. doi:10.1007/s00296-010-1419-0. ISSN 0172-8172. PMID 20354859.

Further reading

• Bare AC, McAnaw MB, Pritchard AE, et al. (July 1996). "Phonophoretic delivery of 10% hydrocortisone through the epidermis of humans as determined by serum cortisol concentrations". Phys Ther. 76 (7): 738–45, discussion 746–9. doi:10.1093/ptj/76.7.738. PMID 8677278.
• Byl NN (June 1995). "The use of ultrasound as an enhancer for transcutaneous drug delivery: phonophoresis". Phys Ther. 75 (6): 539–53. doi:10.1093/ptj/75.6.539. PMID 7770499.
• Gogstetter DS, Goldsmith LA (May 1999). "Treatment of cutaneous sarcoidosis using phonophoresis". J. Am. Acad. Dermatol. 40 (5 Pt 1): 767–9. doi:10.1016/S0190-9622(99)70162-3. PMID 10321609.
• Srbely JZ. "Ultrasound in the management of osteoarthritis: part I: a review of the current literature". JCCA J Can Chiropr Assoc. 52 (1): 30–.
• Hoppenrath T, Ciccone CD (January 2006). "Is there evidence that phonophoresis is more effective than ultrasound in treating pain associated with lateral epicondylitis?". Phys Ther. 86 (1): 136–40. PMID 16386068. Archived from the original on 2009-05-31. Retrieved 2009-05-30.