Pauline Schaap

Pauline Schaap is a Dutch cell biologist and evolutionary biologist. She is Professor of Developmental Signalling at the University of Dundee.[1], a corresponding member of the Royal Netherlands Academy of Arts and Sciences, a Fellow of the Royal Society of Biology, and a Fellow of the Royal Society of Edinburgh.

She studies the evolution of multicellularity and cell differentiation in social amoebae[2].

Biography

Schaap received her PhD in 1987 from the University of Leiden [3]. She was a professor at the University of Leiden until 1999, when she moved to the University of Dundee [4] where she is currently a professor [1]. She became a corresponding member of the Royal Netherlands Academy of Arts and Sciences in 2011 [4][5].

Professional contributions

Schaap and her collaborators established the first molecular phylogeny of the Dictyostelia [6]. That work showed that complex multicellular fruiting bodies had evolved multiple times independently, contrary to what had previously been generally thought [6]. More recently, Schaap and her team showed that the molecular pathway for multicellular development in dictyostelids had evolved from an ancestral encystment pathway present in single-celled amoebae [7][8][9], thus contributing to elucidating the molecular basis for the evolution of multicellularity [10]

gollark: Also, you can just use a wireless card?
gollark: I'd rather be ultra-fancy and have it access some push notification API and send a notification to my phone.
gollark: IRC? What does that have to do with anything?
gollark: ```luapython```
gollark: 0.00001.

References
  1. PSchaap (2013-08-30). "Professor Pauline Schaap FRSE FRSB". School of Life Sciences. Retrieved 2020-05-07.
  2. Schaap, Pauline (2011-02-01). "Evolutionary crossroads in developmental biology: Dictyostelium discoideum". Development. 138 (3): 387–396. doi:10.1242/dev.048934. ISSN 0950-1991. PMID 21205784.
  3. "Pauline Schaap - AcademiaNet". www.academia-net.org. Retrieved 2020-05-07.
  4. "Professor Pauline Schaap FRSE". The Royal Society of Edinburgh. 2020-03-24. Retrieved 2020-05-07.
  5. "Pauline Schaap". Royal Netherlands Academy of Arts and Sciences. Archived from the original on 9 May 2020.
  6. Schaap, Pauline; Winckler, Thomas; Nelson, Michaela; Alvarez-Curto, Elisa; Elgie, Barrie; Hagiwara, Hiromitsu; Cavender, James; Milano-Curto, Alicia; Rozen, Daniel E.; Dingermann, Theodor; Mutzel, Rupert (2006-10-27). "Molecular Phylogeny and Evolution of Morphology in the Social Amoebas". Science. 314 (5799): 661–663. doi:10.1126/science.1130670. ISSN 0036-8075. PMC 2173941. PMID 17068267.
  7. Kawabe, Yoshinori; Schilde, Christina; Du, Qingyou; Schaap, Pauline (2015-04-16). "A Conserved Signalling Pathway for Amoebozoan Encystation that was Co-Opted for Multicellular Development". Scientific Reports. 5 (1): 1–6. doi:10.1038/srep09644. ISSN 2045-2322.
  8. Schaap, Pauline (2016-08-01). "Evolution of developmental signalling in Dictyostelid social amoebas". Current Opinion in Genetics & Development. Developmental mechanisms, patterning and evolution. 39: 29–34. doi:10.1016/j.gde.2016.05.014. ISSN 0959-437X.
  9. Kawabe, Yoshinori; Morio, Takahiro; Tanaka, Yoshimasa; Schaap, Pauline (2018-05-09). "Glycogen synthase kinase 3 promotes multicellular development over unicellular encystation in encysting Dictyostelia". EvoDevo. 9 (1): 12. doi:10.1186/s13227-018-0101-6. ISSN 2041-9139. PMC 5941370. PMID 29760875.
  10. Brunet, Thibaut; King, Nicole (2017-10-23). "The Origin of Animal Multicellularity and Cell Differentiation". Developmental Cell. 43 (2): 124–140. doi:10.1016/j.devcel.2017.09.016. ISSN 1534-5807.
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