PTMS (gene)

Parathymosin is a protein that in humans is encoded by the PTMS gene.[3][4]

PTMS
Identifiers
Aliases	PTMS, ParaT, parathymosin
External IDs	OMIM: 168440 HomoloGene: 136762 GeneCards: PTMS
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12p13.31 Start 6,765,516 bp[1] End 6,770,952 bp[1]
Gene ontology Molecular function • zinc ion binding Cellular component • cell nucleus Biological process • DNA replication • immune system process Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	5763	n/a
Ensembl	ENSG00000159335	n/a
UniProt	P20962	n/a
RefSeq (mRNA)	NM_002824 NM_001330333	n/a
RefSeq (protein)	NP_001317262 NP_002815	n/a
Location (UCSC)	Chr 12: 6.77 – 6.77 Mb	n/a
PubMed search	[2]	n/a
Wikidata
View/Edit Human

References

1. GRCh38: Ensembl release 89: ENSG00000159335 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. Martic G, Karetsou Z, Kefala K, Politou AS, Clapier CR, Straub T, Papamarcaki T (Apr 2005). "Parathymosin affects the binding of linker histone H1 to nucleosomes and remodels chromatin structure". J Biol Chem. 280 (16): 16143–50. doi:10.1074/jbc.M410175200. PMID 15716277.
4. "Entrez Gene: PTMS parathymosin".

Further reading

• Hannappel E, Huff T (2003). "The thymosins. Prothymosin alpha, parathymosin, and beta-thymosins: structure and function". Vitam. Horm. 66: 257–96. PMID 12852257.
• Clinton M, Graeve L, el-Dorry H, et al. (1991). "Evidence for nuclear targeting of prothymosin and parathymosin synthesized in situ". Proc. Natl. Acad. Sci. U.S.A. 88 (15): 6608–12. doi:10.1073/pnas.88.15.6608. PMC 52136. PMID 1862085.
• Panneerselvam C, Caldarella J, Horecker BL (1988). "A radioimmunoassay for parathymosin". J. Immunol. Methods. 104 (1–2): 131–6. doi:10.1016/0022-1759(87)90496-0. PMID 2445824.
• Clinton M, Frangou-Lazaridis M, Panneerselvam C, Horecker BL (1989). "The sequence of human parathymosin deduced from a cloned human kidney cDNA". Biochem. Biophys. Res. Commun. 158 (3): 855–62. doi:10.1016/0006-291X(89)92801-5. PMID 2537638.
• Szabo P, Clinton M, Macera M, Horecker BL (1989). "Localization of the gene coding for parathymosin to chromosome 17 in humans". Cytogenet. Cell Genet. 50 (2–3): 91–2. doi:10.1159/000132730. PMID 2776490.
• Kondili K, Tsolas O, Papamarcaki T (1997). "Selective interaction between parathymosin and histone H1". Eur. J. Biochem. 242 (1): 67–74. doi:10.1111/j.1432-1033.1996.0067r.x. PMID 8954154.
• Bruniquel D, Borie N, Triebel F (1998). "Genomic organization of the human LAG-3/CD4 locus". Immunogenetics. 47 (1): 96–8. doi:10.1007/s002510050332. PMID 9382927.
• Okamoto K, Isohashi F (2000). "Purification and primary structure of a macromolecular-translocation inhibitor II of glucocorticoid-receptor binding to nuclei from rat liver. Inhibitor II is the 11.5-kDa Zn2+-binding protein (parathymosin)". Eur. J. Biochem. 267 (1): 155–62. doi:10.1046/j.1432-1327.2000.00987.x. PMID 10601862.
• Vareli K, Frangou-Lazaridis M, van der Kraan I, et al. (2000). "Nuclear distribution of prothymosin alpha and parathymosin: evidence that prothymosin alpha is associated with RNA synthesis processing and parathymosin with early DNA replication". Exp. Cell Res. 257 (1): 152–61. doi:10.1006/excr.2000.4857. PMID 10854063.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.