PTGES3

Prostaglandin E synthase 3 (cytosolic) is an enzyme that in humans is encoded by the PTGES3 gene.[5]

PTGES3
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPTGES3, P23, TEBP, cPGES, prostaglandin E synthase 3
External IDsOMIM: 607061 MGI: 1929282 HomoloGene: 128197 GeneCards: PTGES3
Gene location (Human)
Chr.Chromosome 12 (human)[1]
Band12q13.3|12Start56,663,341 bp[1]
End56,688,408 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

10728

56351

Ensembl

ENSG00000110958

ENSMUSG00000071072

UniProt

Q15185

Q9R0Q7

RefSeq (mRNA)

NM_019766

RefSeq (protein)

NP_062740

Location (UCSC)Chr 12: 56.66 – 56.69 MbChr 10: 128.06 – 128.08 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

The protein encoded by this gene is also known as p23 which functions as a chaperone which is required for proper functioning of the glucocorticoid and other steroid receptors.[6]

References

  1. GRCh38: Ensembl release 89: ENSG00000110958 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000071072 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: PTGES3 Prostaglandin E synthase 3 (cytosolic)".
  6. Freeman BC, Yamamoto KR (June 2002). "Disassembly of transcriptional regulatory complexes by molecular chaperones". Science. 296 (5576): 2232–2235. doi:10.1126/science.1073051. PMID 12077419.

Further reading


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