PSD3

PH and SEC7 domain-containing protein 3 is a protein that in humans is encoded by the PSD3 gene.[5]

PSD3
Identifiers
Aliases	PSD3, EFA6R, HCA67, EFA6D, pleckstrin and Sec7 domain containing 3
External IDs	OMIM: 614440 MGI: 1918215 HomoloGene: 87257 GeneCards: PSD3
Gene location (Human) Chr. Chromosome 8 (human)[1] Band 8p22 Start 18,527,303 bp[1] End 19,084,730 bp[1]
Gene location (Mouse) Chr. Chromosome 8 (mouse)[2] Band 8|8 B3.2-B3.3 Start 67,689,082 bp[2] End 68,212,027 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • guanyl-nucleotide exchange factor activity • ARF guanyl-nucleotide exchange factor activity Cellular component • synapse • membrane • cell junction • GO:0097483, GO:0097481 postsynaptic density • postsynaptic membrane • cell membrane • ruffle membrane • cell projection Biological process • regulation of ARF protein signal transduction Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	23362	234353
Ensembl	ENSG00000156011	ENSMUSG00000030465
UniProt	Q9NYI0	Q2PFD7
RefSeq (mRNA)	NM_015310 NM_206909 NM_001362819	NM_027626 NM_030263 NM_177698
RefSeq (protein)	NP_056125 NP_996792 NP_001349748	NP_081902 NP_084539 NP_808366
Location (UCSC)	Chr 8: 18.53 – 19.08 Mb	Chr 8: 67.69 – 68.21 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000156011 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000030465 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: PSD3 pleckstrin and Sec7 domain containing 3".

Further reading

• Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Res. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Pils D, Horak P, Gleiss A, et al. (2006). "Five genes from chromosomal band 8p22 are significantly down-regulated in ovarian carcinoma: N33 and EFA6R have a potential impact on overall survival". Cancer. 104 (11): 2417–29. doi:10.1002/cncr.21538. PMID 16270321.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Wang Y, Han KJ, Pang XW, et al. (2002). "Large scale identification of human hepatocellular carcinoma-associated antigens by autoantibodies". J. Immunol. 169 (2): 1102–9. doi:10.4049/jimmunol.169.2.1102. PMID 12097419.
• Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (1): 63–70. doi:10.1093/dnares/6.1.63. PMID 10231032.