PNMA2

Paraneoplastic antigen Ma2 is a protein that in humans is encoded by the PNMA2 gene.[5][6]

PNMA2
Identifiers
Aliases	PNMA2, MA2, MM2, RGAG2, paraneoplastic Ma antigen 2, PNMA family member 2
External IDs	OMIM: 603970 MGI: 2444129 HomoloGene: 5249 GeneCards: PNMA2
Gene location (Human) Chr. Chromosome 8 (human)[1] Band 8p21.2 Start 26,504,701 bp[1] End 26,514,092 bp[1]
Gene location (Mouse) Chr. Chromosome 14 (mouse)[2] Band 14|14 D1 Start 66,911,170 bp[2] End 66,921,023 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001948 protein binding Cellular component • cell nucleus • nucleolus Biological process • positive regulation of apoptotic process Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	10687	239157
Ensembl	ENSG00000240694	ENSMUSG00000046204
UniProt	Q9UL42	Q8BHK0
RefSeq (mRNA)	NM_007257	NM_175498
RefSeq (protein)	NP_009188	NP_780707
Location (UCSC)	Chr 8: 26.5 – 26.51 Mb	Chr 14: 66.91 – 66.92 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000240694 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000046204 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Voltz R, Gultekin SH, Rosenfeld MR, Gerstner E, Eichen J, Posner JB, Dalmau J (Jun 1999). "A serologic marker of paraneoplastic limbic and brain-stem encephalitis in patients with testicular cancer". N Engl J Med. 340 (23): 1788–95. doi:10.1056/NEJM199906103402303. PMID 10362822.
6. "Entrez Gene: PNMA2 paraneoplastic antigen MA2".

Further reading

• Hillier LD, Lennon G, Becker M, et al. (1997). "Generation and analysis of 280,000 human expressed sequence tags". Genome Res. 6 (9): 807–28. doi:10.1101/gr.6.9.807. PMID 8889549.
• Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 5 (6): 355–64. doi:10.1093/dnares/5.6.355. PMID 10048485.
• Dalmau J, Gultekin SH, Voltz R, et al. (1999). "Ma1, a novel neuron- and testis-specific protein, is recognized by the serum of patients with paraneoplastic neurological disorders". Brain. 122 (1): 27–39. doi:10.1093/brain/122.1.27. PMID 10050892.
• Rosenfeld MR, Eichen JG, Wade DF, et al. (2001). "Molecular and clinical diversity in paraneoplastic immunity to Ma proteins". Ann. Neurol. 50 (3): 339–48. doi:10.1002/ana.1288. PMID 11558790.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.