PDZRN3

PDZ domain-containing RING finger protein 3 is a protein that in humans is encoded by the PDZRN3 gene.[5][6]

PDZRN3
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1UHP, 1WH1
Identifiers
Aliases	PDZRN3, LNX3, SEMACAP3, SEMCAP3, PDZ domain containing ring finger 3
External IDs	OMIM: 609729 MGI: 1933157 HomoloGene: 10328 GeneCards: PDZRN3
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3p13 Start 73,382,431 bp[1] End 73,624,941 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6|6 D3 Start 101,149,609 bp[2] End 101,377,897 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • zinc ion binding • metal ion binding • GO:1904264, GO:1904822, GO:0090622, GO:0090302 ubiquitin protein ligase activity • ubiquitin-protein transferase activity • transferase activity Cellular component • neuromuscular junction • cell nucleus • nucleoplasm • cytosol • cytoplasm • cell junction • synapse Biological process • neuromuscular junction development • protein ubiquitination Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	23024	55983
Ensembl	ENSG00000121440	ENSMUSG00000035357
UniProt	Q9UPQ7	Q69ZS0
RefSeq (mRNA)	NM_015009 NM_001303139 NM_001303140 NM_001303141 NM_001303142	NM_018884
RefSeq (protein)	NP_001290068 NP_001290069 NP_001290070 NP_001290071 NP_055824	NP_061372
Location (UCSC)	Chr 3: 73.38 – 73.62 Mb	Chr 6: 101.15 – 101.38 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000121440 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000035357 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Kikuno R, Nagase T, Ishikawa K, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Oct 1999). "Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (3): 197–205. doi:10.1093/dnares/6.3.197. PMID 10470851.
6. "Entrez Gene: PDZRN3 PDZ domain containing RING finger 3".

Further reading

• Bach I, Rodriguez-Esteban C, Carrière C, et al. (1999). "RLIM inhibits functional activity of LIM homeodomain transcription factors via recruitment of the histone deacetylase complex". Nat. Genet. 22 (4): 394–9. doi:10.1038/11970. PMID 10431247.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Katoh M, Katoh M (2004). "Identification and characterization of PDZRN3 and PDZRN4 genes in silico". Int. J. Mol. Med. 13 (4): 607–13. doi:10.3892/ijmm.13.4.607. PMID 15010864.
• Hassel S, Eichner A, Yakymovych M, et al. (2004). "Proteins associated with type II bone morphogenetic protein receptor (BMPR-II) and identified by two-dimensional gel electrophoresis and mass spectrometry". Proteomics. 4 (5): 1346–58. doi:10.1002/pmic.200300770. PMID 15188402.
• Santin AD, Zhan F, Bellone S, et al. (2004). "Gene expression profiles in primary ovarian serous papillary tumors and normal ovarian epithelium: identification of candidate molecular markers for ovarian cancer diagnosis and therapy". Int. J. Cancer. 112 (1): 14–25. doi:10.1002/ijc.20408. PMID 15305371.
• Meyer G, Varoqueaux F, Neeb A, et al. (2005). "The complexity of PDZ domain-mediated interactions at glutamatergic synapses: a case study on neuroligin". Neuropharmacology. 47 (5): 724–33. doi:10.1016/j.neuropharm.2004.06.023. PMID 15458844.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.