PARVG

Gamma-parvin is a protein that in humans is encoded by the PARVG gene.[5][6]

PARVG
Identifiers
Aliases	PARVG, parvin gamma
External IDs	OMIM: 608122 MGI: 2158329 HomoloGene: 11151 GeneCards: PARVG
Gene location (Human) Chr. Chromosome 22 (human)[1] Band 22q13.31 Start 44,172,956 bp[1] End 44,219,533 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15|15 E2 Start 84,324,026 bp[2] End 84,342,978 bp[2]
Gene ontology Molecular function • actin binding • GO:0001948 protein binding Cellular component • cytoplasm • cell junction • cell membrane • cytoskeleton • membrane • focal adhesion • actin cytoskeleton Biological process • actin cytoskeleton reorganization • cell-matrix adhesion • cell adhesion • establishment or maintenance of cell polarity • cell projection assembly • substrate adhesion-dependent cell spreading Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	64098	64099
Ensembl	ENSG00000138964	ENSMUSG00000022439
UniProt	Q9HBI0	Q9ERD8
RefSeq (mRNA)	NM_001137605 NM_001137606 NM_001254741 NM_001254742 NM_001254743 NM_022141	NM_001162500 NM_022321
RefSeq (protein)	NP_001131077 NP_071424	NP_001155972 NP_071716
Location (UCSC)	Chr 22: 44.17 – 44.22 Mb	Chr 15: 84.32 – 84.34 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Members of the parvin family, including PARVG, PARVA and PARVB, are actin-binding proteins associated with focal contacts.[supplied by OMIM][6]

References

1. GRCh38: Ensembl release 89: ENSG00000138964 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000022439 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Olski TM, Noegel AA, Korenbaum E (Feb 2001). "Parvin, a 42 kDa focal adhesion protein, related to the alpha-actinin superfamily". J Cell Sci. 114 (Pt 3): 525–38. PMID 11171322.
6. "Entrez Gene: PARVG parvin, gamma".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Dunham I, Shimizu N, Roe BA, et al. (1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–95. doi:10.1038/990031. PMID 10591208.
• Korenbaum E, Olski TM, Noegel AA (2002). "Genomic organization and expression profile of the parvin family of focal adhesion proteins in mice and humans". Gene. 279 (1): 69–79. doi:10.1016/S0378-1119(01)00743-0. PMID 11722847.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Collins JE, Goward ME, Cole CG, et al. (2003). "Reevaluating human gene annotation: a second-generation analysis of chromosome 22". Genome Res. 13 (1): 27–36. doi:10.1101/gr.695703. PMC 430954. PMID 12529303.
• Collins JE, Wright CL, Edwards CA, et al. (2005). "A genome annotation-driven approach to cloning the human ORFeome". Genome Biol. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMC 545604. PMID 15461802.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Alonso ME, Bello MJ, de Campos JM, et al. (2005). "No evidence of INI1hSNF5 (SMARCB1) and PARVG point mutations in oligodendroglial neoplasms". Cancer Genet. Cytogenet. 160 (2): 169–73. doi:10.1016/j.cancergencyto.2004.12.020. PMID 15993274.
• Yoshimi R, Yamaji S, Suzuki A, et al. (2006). "The gamma-parvin-integrin-linked kinase complex is critically involved in leukocyte-substrate interaction". J. Immunol. 176 (6): 3611–24. doi:10.4049/jimmunol.176.6.3611. PMID 16517730.