p-Chlorocresol

p-Chlorocresol
Names
	IUPAC name 4-Chloro-3-methylphenol
	Other names p-chloro-m-cresol; PCMC; Preventol; CMK
Identifiers
CAS Number	59-50-7 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:34395;
ChEMBL	ChEMBL1230222 ;
ChemSpider	21106018 ;
ECHA InfoCard	100.000.392
EC Number	200-431-6;
KEGG	C14331; D03468;
PubChem CID	1732;
RTECS number	GO7100000;
UNII	36W53O7109 ;
UN number	2669
CompTox Dashboard (EPA)	DTXSID4021717 ;
	InChI InChI=1S/C7H7ClO/c1-5-4-6(9)2-3-7(5)8/h2-4,9H,1H3 Key: CFKMVGJGLGKFKI-UHFFFAOYSA-N ; InChI=1/C7H7ClO/c1-5-4-6(9)2-3-7(5)8/h2-4,9H,1H3 Key: CFKMVGJGLGKFKI-UHFFFAOYAE;
	SMILES Oc1ccc(Cl)c(C)c1;
Properties
Chemical formula	C7H7ClO
Molar mass	142.58 g·mol−1
Appearance	White/pink solid
Odor	Phenolic
Density	1.37 g/cm3 (20 °C)
Melting point	55.55 °C (131.99 °F; 328.70 K)
Boiling point	235 °C (455 °F; 508 K)
Solubility in water	3.8 g/l at 20 °C (in water)
Hazards
GHS pictograms
GHS Signal word	Danger
GHS hazard statements	H302, H314, H317, H318, H335, H400, H412
GHS precautionary statements	P260, P261, P264, P270, P271, P272, P273, P280, P301+312, P301+330+331, P302+352, P303+361+353, P304+340, P305+351+338, P310, P312, P321, P330, P333+313, P363, P391, P403+233, P405, P501
Flash point	118 °C (244 °F; 391 K)
Related compounds
Related compounds	Chloroxylenol (4-chloro-3,5-dimethylphenol)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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	Infobox references

p-Chlorocresol is the organic compound with the formula ClC₆H₄OH. It is a monochlorinated m-cresol. It is a white or colorless solid that is only slightly soluble in water. As a solution in alcohol and in combination with other phenols, it is used as an antiseptic and preservative.[1][2] It is a moderate allergen for sensitive skin.[3]

p-Chlorocresol is prepared by chlorination of m-cresol.[4][5]

Safety

With LD₅₀(oral, rat) of 5129 mg/kg, it is weakly toxic.[4]

gollark: Huge inconsistency, being bodged together over probably decades.

gollark: They are not really the same thing.

gollark: Don't use it, it's pure horror and insanity.

gollark: No.

gollark: Oh, right, so you need to put that there and run it unconditionally.

References

Susan C Smolinske (1992), Handbook of Food, Drug, and Cosmetic Excipients, p. 87
C. Glen Mayhall (2004), Hospital Epidemiology and Infection Control, p. 1741
Howard I. Maibach (2001), Toxicology of Skin, p. 339
Helmut Fiege; Heinz-Werner Voges; Toshikazu Hamamoto; Sumio Umemura; Tadao Iwata; Hisaya Miki; Yasuhiro Fujita; Hans-Josef Buysch; Dorothea Garbe (2007). "Phenol Derivatives". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a19_313.
Commission, British Pharmacopoeia (2009), "Phenoxyethanol", British Pharmacopoeia, 2, ISBN 978-0-11-322799-0

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[1] Susan C Smolinske (1992), Handbook of Food, Drug, and Cosmetic Excipients, p. 87

[2] C. Glen Mayhall (2004), Hospital Epidemiology and Infection Control, p. 1741

[3] Howard I. Maibach (2001), Toxicology of Skin, p. 339

[a-4] Helmut Fiege; Heinz-Werner Voges; Toshikazu Hamamoto; Sumio Umemura; Tadao Iwata; Hisaya Miki; Yasuhiro Fujita; Hans-Josef Buysch; Dorothea Garbe (2007). "Phenol Derivatives". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a19_313.

[5] Commission, British Pharmacopoeia (2009), "Phenoxyethanol", British Pharmacopoeia, 2, ISBN 978-0-11-322799-0

p-Chlorocresol

Safety

See also

References