OXR1

Oxidation resistance protein 1 is a protein that in humans is encoded by the OXR1 gene.[5][6]

OXR1
Identifiers
Aliases	OXR1, TLDC3, Nbla00307, oxidation resistance 1, CHEGDD
External IDs	OMIM: 605609 MGI: 2179326 HomoloGene: 24993 GeneCards: OXR1
Gene location (Human) Chr. Chromosome 8 (human)[1] Band 8q23.1 Start 106,359,476 bp[1] End 106,752,694 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15|15 B3.1 Start 41,447,482 bp[2] End 41,861,048 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • oxidoreductase activity • GO:0001948 protein binding • molecular function Cellular component • nucleolus • mitochondrion • cellular component • nucleoplasm • intracellular membrane-bounded organelle Biological process • negative regulation of neuron apoptotic process • oxidation-reduction process • response to oxidative stress • cellular response to hydroperoxide • adult walking behavior • neuron apoptotic process • negative regulation of cellular response to oxidative stress • negative regulation of peptidyl-cysteine S-nitrosylation • negative regulation of oxidative stress-induced neuron death Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	55074	170719
Ensembl	ENSG00000164830	ENSMUSG00000022307
UniProt	Q8N573	Q4KMM3
RefSeq (mRNA)	NM_001198532 NM_001198533 NM_001198534 NM_001198535 NM_018002 NM_181354	NM_001130163 NM_001130164 NM_001130165 NM_001130166 NM_130885 NM_001358976 NM_001358977 NM_001358978
RefSeq (protein)	NP_001185461 NP_001185462 NP_001185463 NP_001185464 NP_060472 NP_851999	NP_001123635 NP_001123636 NP_001123637 NP_001123638 NP_570955 NP_001345905 NP_001345906 NP_001345907
Location (UCSC)	Chr 8: 106.36 – 106.75 Mb	Chr 15: 41.45 – 41.86 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000164830 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000022307 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Volkert MR, Elliott NA, Housman DE (Jan 2001). "Functional genomics reveals a family of eukaryotic oxidation protection genes". Proc Natl Acad Sci U S A. 97 (26): 14530–5. doi:10.1073/pnas.260495897. PMC 18953. PMID 11114193.
6. "Entrez Gene: OXR1 oxidation resistance 1".

Further reading

• Ohira M, Morohashi A, Nakamura Y, et al. (2003). "Neuroblastoma oligo-capping cDNA project: toward the understanding of the genesis and biology of neuroblastoma". Cancer Lett. 197 (1–2): 63–8. doi:10.1016/S0304-3835(03)00085-5. PMID 12880961.
• Durand M, Kolpak A, Farrell T, et al. (2007). "The OXR domain defines a conserved family of eukaryotic oxidation resistance proteins". BMC Cell Biol. 8: 13. doi:10.1186/1471-2121-8-13. PMC 1847813. PMID 17391516.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Elliott NA, Volkert MR (2004). "Stress Induction and Mitochondrial Localization of Oxr1 Proteins in Yeast and Humans". Mol. Cell. Biol. 24 (8): 3180–7. doi:10.1128/MCB.24.8.3180-3187.2004. PMC 381681. PMID 15060142.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.