Nonvolatile acid

A nonvolatile acid (also known as a fixed acid or metabolic acid) is an acid produced in the body from sources other than carbon dioxide, and is not excreted by the lungs. They are produced from e.g. an incomplete metabolism of carbohydrates, fats, and proteins. All acids produced in the body are nonvolatile except carbonic acid, which is the sole volatile acid. Common nonvolatile acids in humans are lactic acid, phosphoric acid, sulfuric acid, acetoacetic acid, and beta-hydroxybutyric acid. Humans produce about 1–1.5 mmoles of H+ per kilogram per day.[1] The nonvolatile acids are excreted by the kidneys. Lactic acid is usually completely metabolized by the body, and is thus not excreted from the body.

Reactions

The following reactions result in nonvolatile acids. Such reactions do not take place in volatile acids for obvious reasons.


e.g. methionine or cysteine → Urea + CO2 + H2SO4 → 2H+ + SO42−

  • phosphorus-containing compound metabolism[2] → H3PO4 → H+ + H2PO4−
  • cationic amino acid oxidation:[2]

e.g. lysine or arginine →Urea + CO2 + H2O + H+

  • Non-metabolizable organic acid production:[2]

HA → H+ + A−

gollark: Idea: COMPLETELY WIN code guessing by just overwriting the test suite.
gollark: Just live-patch your code in memory to fix it.
gollark: Mostly, you just need to use a bunch of intermediate instances to receive, reduce and filter everything.
gollark: I mean, it's not like *all* the subjects died.
gollark: You *can*, but loading all the information - much of it conflicting - into your brain *has* been known to lead to a few moderately problematic side effects.

See also

References
  1. "Acid-Base Physiology". Retrieved 2007-05-30.
  2. Walter F., PhD. Boron. Medical Physiology: A Cellular And Molecular Approaoch. Elsevier/Saunders. ISBN 1-4160-2328-3. Page 846
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.