Nolatrexed

Nolatrexed is a thymidylate synthase inhibitor.[1][2]

Nolatrexed

Names
IUPAC name 2-Amino-6-methyl-5-(4-pyridylthio)-1H-quinazolin-4-one
Identifiers
CAS Number	147149-76-6^Y
3D model (JSmol)	Interactive image
ChemSpider	97268^N
PubChem CID	108189
UNII	K75ZUN743Q^Y
CompTox Dashboard (EPA)	DTXSID3048281
InChI InChI=1S/C14H12N4OS/c1-8-2-3-10-11(13(19)18-14(15)17-10)12(8)20-9-4-6-16-7-5-9/h2-7H,1H3,(H3,15,17,18,19)^N Key: XHWRWCSCBDLOLM-UHFFFAOYSA-N^N InChI=1/C14H12N4OS/c1-8-2-3-10-11(13(19)18-14(15)17-10)12(8)20-9-4-6-16-7-5-9/h2-7H,1H3,(H3,15,17,18,19) Key: XHWRWCSCBDLOLM-UHFFFAOYAK
SMILES CC1=C(C2=C(C=C1)NC(=NC2=O)N)SC3=CC=NC=C3
Properties
Chemical formula	C14H12N4OS
Molar mass	284.34 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is ^YN ?)
Infobox references

References

1. Hughes AN, Rafi I, Griffin MJ, et al. (January 1999). "Phase I studies with the nonclassical antifolate nolatrexed dihydrochloride (AG337, THYMITAQ) administered orally for 5 days". Clin. Cancer Res. 5 (1): 111–8. PMID 9918208.
2. "Nolatrexed". PubChem.gov. Pub Chem. Retrieved 12 August 2014.