Nimbin (chemical)

Nimbin
Names
	IUPAC name Methyl (2R,3aR,4aS,5R,5aR,6R,9aR,10S,10aR)-5-(acetyloxy)-2-(furan-3-yl)-10-(2-methoxy-2-oxoethyl)-1,6,9a,10a-tetramethyl-9-oxo-3,3a,4a,5,5a,6,9,9a,10,10a-decahydro-2H-cyclopenta[b]naphtho[2,3-d]furan-6-carboxylate
Identifiers
CAS Number	5945-86-8 ;
3D model (JSmol)	Interactive image;
ChemSpider	97160;
ECHA InfoCard	100.106.899
PubChem CID	108058;
UNII	N4CTG7K9IU ;
CompTox Dashboard (EPA)	DTXSID80208168 ;
	InChI InChI=1S/C30H36O9/c1-15-18(17-9-11-37-14-17)12-19-23(15)30(5)20(13-22(33)35-6)29(4)21(32)8-10-28(3,27(34)36-7)25(29)24(26(30)39-19)38-16(2)31/h8-11,14,18-20,24-26H,12-13H2,1-7H3/t18-,19-,20-,24-,25+,26-,28-,29+,30-/m1/s1 Key: NHOIBRJOQAYBJT-IMGVWCFESA-N; InChI=1/C30H36O9/c1-15-18(17-9-11-37-14-17)12-19-23(15)30(5)20(13-22(33)35-6)29(4)21(32)8-10-28(3,27(34)36-7)25(29)24(26(30)39-19)38-16(2)31/h8-11,14,18-20,24-26H,12-13H2,1-7H3/t18-,19-,20-,24-,25+,26-,28-,29+,30-/m1/s1 Key: NHOIBRJOQAYBJT-IMGVWCFEBM;
	SMILES O=C1\C=C/[C@@](C(=O)OC)([C@H]4[C@]1([C@H]([C@@]3(\C5=C(/C)[C@H](c2ccoc2)C[C@H]5O[C@@H]3[C@@H]4OC(=O)C)C)CC(=O)OC)C)C;
Properties
Chemical formula	C30H36O9
Molar mass	540.609 g·mol−1
Melting point	205 °C (401 °F; 478 K)[1]
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
	Infobox references

Nimbin is a triterpenoid isolated from Neem. Nimbin is thought to be responsible for much of the biological activities of neem oil, and is reported to have anti-inflammatory, antipyretic, fungicidal, antihistamine and antiseptic properties.[2]

References

Siddiqui, Salimuzzaman (1945). "Utilization of nim oil and its bitter constituents (nimbidin series) in the pharmaceutical industry". Journal of Scientific & Industrial Research. 4: 5–10.
W. Kraus, "Biologically active ingredients-azadirachtin and other triterpenoids", in: H. Schutterer (Ed.), The Neem Tree Azadirachta indica A. Juss and Other Meliaceous Plants, Weinheim, New York, 1995, p 35-88

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