Neisseria lactamica
Neisseria lactamica is a gram-negative diplococcus bacterium. It is strictly a commensal species of the nasopharynx. Uniquely among the Neisseria they are able to produce β-D-galactosidase and ferment lactose.[1]
Neisseria lactamica | |
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Class: | Beta Proteobacteria |
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Species: | N. lactamica |
Binomial name | |
Neisseria lactamica | |
This species is most commonly carried by young children. There is an inverse relationship between colonisation by N. lactamica and Neisseria meningitidis.[2] Carriage of N. lactamica has been associated with decreased incidence of invasive meningococcal disease.[3] However, resistance to penicillin and other beta-lactams may be transmitted from commensal neisseriae such as Neisseria lactamica to disease causing Neisseria meningitidis by the process of genetic transformation.[4]
References
- Hollis DG, Wiggins GL, Weaver RE (1969). "Neisseria lactamicus sp. n., a lactose-fermenting species resembling Neisseria meningitidis". Appl Microbiology. 17 (1): 71–7. PMC 377615. PMID 4975454.
- Gold R, Goldschneider I, Lepow ML, Draper TF, Randolph M (1978). "Carriage of Neisseria meningitidis and Neisseria lactamica in infants and children". J Infect Dis. 137 (2): 112–21. doi:10.1093/infdis/137.2.112. PMID 415097.
- Coen PG, Cartwright K, Stuart J (2000). "Mathematical modelling of infection and disease due to Neisseria meningitidis and Neisseria lactamica". Int J Epidemiol. 29 (1): 180–8. doi:10.1093/ije/29.1.180. PMID 10750621.
- Saez-Nieto JA, Lujan R, Martinez-Suarez JV, Berron S, Vazquez JA, Viñas M, Campos J (1990). "Neisseria lactamica and Neisseria polysaccharea as possible sources of meningococcal beta-lactam resistance by genetic transformation". Antimicrob. Agents Chemother. 34 (11): 2269–72. doi:10.1128/aac.34.11.2269. PMC 172037. PMID 2127349.
External links
- Genome sequence of Neisseria lactamica (an ST640 strain). Published on the Wellcome Trust Sanger Institute ftp server.
- Sequence data from the Neisseria lactamica Y92-1009 genome sequencing project.
- Sequence data from the Neisseria lactamica ATCC 23970 genome sequencing project.
- Type strain of Neisseria lactamica at BacDive - the Bacterial Diversity Metadatabase
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