NUFIP1

Nuclear fragile X mental retardation-interacting protein 1 is a protein that in humans is encoded by the NUFIP1 gene.[5][6][7]

NUFIP1
Identifiers
AliasesNUFIP1, NUFIP, bA540M5.1, FMR1 interacting protein 1, nuclear FMR1 interacting protein 1, Rsa1
External IDsOMIM: 604354 MGI: 1351474 HomoloGene: 8216 GeneCards: NUFIP1
Gene location (Human)
Chr.Chromosome 13 (human)[1]
Band13q14.12Start44,939,249 bp[1]
End44,989,471 bp[1]
RNA expression pattern




More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

26747

27275

Ensembl

ENSG00000083635

ENSMUSG00000022009

UniProt

Q9UHK0

Q9QXX8

RefSeq (mRNA)

NM_012345

NM_013745

RefSeq (protein)

NP_036477

NP_038773

Location (UCSC)Chr 13: 44.94 – 44.99 MbChr 14: 76.11 – 76.14 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

NUFIP1 has been shown to interact with:

gollark: Not "oops, we accidentally made something exactly like a human but it's in a computer and it doesn't like us".
gollark: The main thing we probably have to worry about is misaligned things being programmed with goals like "ensure there is no mess on the floor" removing the entire floor, and such.
gollark: ......
gollark: Building in resentment and such would actually be harder than just not doing that.
gollark: ...

References

  1. GRCh38: Ensembl release 89: ENSG00000083635 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000022009 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Bardoni B, Schenck A, Mandel JL (Jan 2000). "A novel RNA-binding nuclear protein that interacts with the fragile X mental retardation (FMR1) protein". Hum Mol Genet. 8 (13): 2557–66. doi:10.1093/hmg/8.13.2557. PMID 10556305.
  6. Bardoni B, Giglio S, Schenck A, Rocchi M, Mandel JL (Aug 2000). "Assignment of NUFIP1 (nuclear FMRP interacting protein 1) gene to chromosome 13q14 and assignment of a pseudogene to chromosome 6q12". Cytogenet Cell Genet. 89 (1–2): 11–3. doi:10.1159/000015580. PMID 10894927.
  7. "Entrez Gene: NUFIP1 nuclear fragile X mental retardation protein interacting protein 1".
  8. Cabart P, Chew HK, Murphy S (Jul 2004). "BRCA1 cooperates with NUFIP and P-TEFb to activate transcription by RNA polymerase II". Oncogene. 23 (31): 5316–29. doi:10.1038/sj.onc.1207684. PMID 15107825.
  9. Bardoni B, Castets M, Huot ME, Schenck A, Adinolfi S, Corbin F, Pastore A, Khandjian EW, Mandel JL (Jul 2003). "82-FIP, a novel FMRP (fragile X mental retardation protein) interacting protein, shows a cell cycle-dependent intracellular localization". Hum. Mol. Genet. 12 (14): 1689–98. doi:10.1093/hmg/ddg181. PMID 12837692.

Further reading


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