NSMCE4A

Non-SMC element 4 homolog A is a protein that in humans is encoded by the NSMCE4A gene.[5][6]

NSMCE4A
Identifiers
Aliases	NSMCE4A, C10orf86, NS4EA, NSE4A, NSE4 homolog A, SMC5-SMC6 complex component
External IDs	OMIM: 612987 MGI: 1915122 HomoloGene: 9745 GeneCards: NSMCE4A
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10q26.13 Start 121,957,091 bp[1] End 121,975,217 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 F3 Start 130,532,526 bp[2] End 130,573,118 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001948 protein binding Cellular component • chromosome, telomeric region • Smc5-Smc6 complex • cell nucleus • chromosome • nucleoplasm • nuclear body Biological process • DNA recombination • DNA repair • positive regulation of response to DNA damage stimulus • cellular response to DNA damage stimulus Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	54780	67872
Ensembl	ENSG00000107672	ENSMUSG00000040331
UniProt	Q9NXX6	n/a
RefSeq (mRNA)	NM_001167865 NM_017615	NM_001162855
RefSeq (protein)	NP_001161337 NP_060085	n/a
Location (UCSC)	Chr 10: 121.96 – 121.98 Mb	Chr 7: 130.53 – 130.57 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000107672 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000040331 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Hu B, Liao C, Millson SH, Mollapour M, Prodromou C, Pearl LH, Piper PW, Panaretou B (Mar 2005). "Qri2/Nse4, a component of the essential Smc5/6 DNA repair complex". Mol Microbiol. 55 (6): 1735–50. doi:10.1111/j.1365-2958.2005.04531.x. PMID 15752197.
6. "Entrez Gene: NSMCE4A non-SMC element 4 homolog A (S. cerevisiae)".

Further reading

• Wan D, Gong Y, Qin W, et al. (2004). "Large-scale cDNA transfection screening for genes related to cancer development and progression". Proc. Natl. Acad. Sci. U.S.A. 101 (44): 15724–9. doi:10.1073/pnas.0404089101. PMC 524842. PMID 15498874.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. doi:10.1038/nature02462. PMID 15164054.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.