NRBP1

Nuclear receptor-binding protein is a protein that in humans is encoded by the NRBP1 gene.[5][6][7]

NRBP1
Identifiers
Aliases	NRBP1, BCON3, MADM, MUDPNP, NRBP, nuclear receptor binding protein 1
External IDs	OMIM: 606010 MGI: 2183436 HomoloGene: 8373 GeneCards: NRBP1
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2p23.3 Start 27,427,790 bp[1] End 27,442,259 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 B1 Start 31,240,864 bp[2] End 31,251,566 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • protein kinase activity • GO:0001948 protein binding • ATP binding • protein serine/threonine kinase activity • protein homodimerization activity Cellular component • cytoplasm • cell projection • cell cortex • membrane • endomembrane system • lamellipodium • nucleoplasm • cytosol Biological process • ER to Golgi vesicle-mediated transport • transcription initiation from RNA polymerase II promoter • GO:0007243 intracellular signal transduction • protein phosphorylation Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	29959	192292
Ensembl	ENSG00000115216	ENSMUSG00000029148
UniProt	Q9UHY1	Q99J45
RefSeq (mRNA)	NM_013392 NM_001321357 NM_001321358 NM_001321359 NM_001321361 NM_001321362 NM_001321363	NM_147201 NM_001347326
RefSeq (protein)	NP_001308286 NP_001308287 NP_001308288 NP_001308290 NP_001308291 NP_001308292 NP_037524	NP_001334255 NP_671734
Location (UCSC)	Chr 2: 27.43 – 27.44 Mb	Chr 5: 31.24 – 31.25 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000115216 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000029148 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Hooper JD, Baker E, Ogbourne SM, Sutherland GR, Antalis TM (Jul 2000). "Cloning of the cDNA and localization of the gene encoding human NRBP, a ubiquitously expressed, multidomain putative adapter protein". Genomics. 66 (1): 113–8. doi:10.1006/geno.2000.6167. PMID 10843813.
6. De Langhe S, Haataja L, Senadheera D, Groffen J, Heisterkamp N (Apr 2002). "Interaction of the small GTPase Rac3 with NRBP, a protein with a kinase-homology domain". Int J Mol Med. 9 (5): 451–9. doi:10.3892/ijmm.9.5.451. PMID 11956649.
7. "Entrez Gene: NRBP1 nuclear receptor binding protein 1".

Further reading

• Martinez P (1976). "[A nurse with the drug addicts]". Revue de l'Infirmière. 26 (7): 557–62. PMID 1048605.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Lim R, Winteringham LN, Williams JH, et al. (2002). "MADM, a novel adaptor protein that mediates phosphorylation of the 14-3-3 binding site of myeloid leukemia factor 1". J. Biol. Chem. 277 (43): 40997–1008. doi:10.1074/jbc.M206041200. PMID 12176995.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Chua JJ, Ng MM, Chow VT (2004). "The non-structural 3 (NS3) protein of dengue virus type 2 interacts with human nuclear receptor binding protein and is associated with alterations in membrane structure". Virus Res. 102 (2): 151–63. doi:10.1016/j.virusres.2004.01.025. PMID 15084397.
• Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell. Proteomics. 3 (11): 1093–101. doi:10.1074/mcp.M400085-MCP200. PMID 15345747.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature. 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
• Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.
• Wang H, Sun X, Luo Y, et al. (2006). "Adapter protein NRBP associates with Jab1 and negatively regulates AP-1 activity". FEBS Lett. 580 (25): 6015–21. doi:10.1016/j.febslet.2006.10.002. PMID 17052710.
• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.