NRBF2

Nuclear receptor-binding factor 2 is a protein that in humans is encoded by the NRBF2 gene.[5][6]

NRBF2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4ZEY
Identifiers
Aliases	NRBF2, COPR1, COPR2, NRBF-2, COPR, nuclear receptor binding factor 2
External IDs	OMIM: 616477 MGI: 1354950 HomoloGene: 41473 GeneCards: NRBF2
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10q21.3 Start 63,133,247 bp[1] End 63,155,031 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10|10 B5.1 Start 67,266,689 bp[2] End 67,285,305 bp[2]
Gene ontology Molecular function • GO:0001948 protein binding Cellular component • cytoplasm • phosphatidylinositol 3-kinase complex, class III • autophagosome • cell nucleus • nucleoplasm • cytoplasmic vesicle Biological process • transcription initiation from RNA polymerase II promoter • regulation of transcription, DNA-templated • response to endoplasmic reticulum stress • transcription, DNA-templated • regulation of lipid kinase activity • autophagy Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	29982	641340
Ensembl	ENSG00000148572	ENSMUSG00000075000
UniProt	Q96F24	Q8VCQ3
RefSeq (mRNA)	NM_001282405 NM_030759	NM_001036293
RefSeq (protein)	NP_001269334 NP_110386	NP_001031370
Location (UCSC)	Chr 10: 63.13 – 63.16 Mb	Chr 10: 67.27 – 67.29 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000148572 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000075000 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Yasumo H, Masuda N, Furusawa T, Tsukamoto T, Sadano H, Osumi T (May 2000). "Nuclear receptor binding factor-2 (NRBF-2), a possible gene activator protein interacting with nuclear hormone receptors". Biochim Biophys Acta. 1490 (1–2): 189–97. doi:10.1016/S0167-4781(99)00244-4. PMID 10786636.
6. "Entrez Gene: NRBF2 nuclear receptor binding factor 2".

Further reading

• Adams MD, Kerlavage AR, Fleischmann RD, et al. (1995). "Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence" (PDF). Nature. 377 (6547 Suppl): 3–174. PMID 7566098.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Flores AM, Li L, Aneskievich BJ (2005). "Isolation and functional analysis of a keratinocyte-derived, ligand-regulated nuclear receptor comodulator". J. Invest. Dermatol. 123 (6): 1092–101. doi:10.1111/j.0022-202X.2004.23424.x. PMID 15610520.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.