NDUFC1

NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial is an enzyme that in humans is encoded by the NDUFC1 gene.[5][6][7]

NDUFC1
Identifiers
Aliases	NDUFC1, KFYI, NADH:ubiquinone oxidoreductase subunit C1
External IDs	OMIM: 603844 MGI: 1913627 HomoloGene: 1865 GeneCards: NDUFC1
Gene location (Human) Chr. Chromosome 4 (human)[1] Band 4q31.1 Start 139,266,880 bp[1] End 139,302,551 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 C Start 51,404,677 bp[2] End 51,408,988 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • NADH dehydrogenase (ubiquinone) activity Cellular component • integral component of membrane • mitochondrial inner membrane • electron transport • membrane • mitochondrion • mitochondrial respiratory chain complex I Biological process • oxidation-reduction process • mitochondrial electron transport, NADH to ubiquinone • mitochondrial respiratory chain complex I assembly Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	4717	66377
Ensembl	ENSG00000109390	ENSMUSG00000037152
UniProt	O43677	Q9CQY9
RefSeq (mRNA)	NM_002494 NM_001184986 NM_001184987 NM_001184988 NM_001184989 NM_001184990 NM_001184991	NM_025523
RefSeq (protein)	NP_001171915 NP_001171916 NP_001171917 NP_001171918 NP_001171919 NP_001171920 NP_002485	NP_079799
Location (UCSC)	Chr 4: 139.27 – 139.3 Mb	Chr 3: 51.4 – 51.41 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000109390 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000037152 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Ton C, Hwang DM, Dempsey AA, Liew CC (Jan 1998). "Identification and primary structure of five human NADH-ubiquinone oxidoreductase subunits". Biochem Biophys Res Commun. 241 (2): 589–94. doi:10.1006/bbrc.1997.7707. PMID 9425316.
6. Emahazion T, Beskow A, Gyllensten U, Brookes AJ (Nov 1998). "Intron based radiation hybrid mapping of 15 complex I genes of the human electron transport chain". Cytogenet Cell Genet. 82 (1–2): 115–9. doi:10.1159/000015082. PMID 9763677.
7. "Entrez Gene: NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa".

Further reading

• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
• Loeffen JL, Triepels RH, van den Heuvel LP, et al. (1999). "cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed". Biochem. Biophys. Res. Commun. 253 (2): 415–22. doi:10.1006/bbrc.1998.9786. PMID 9878551.
• Mao M, Fu G, Wu JS, et al. (1998). "Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full-length cDNA cloning". Proc. Natl. Acad. Sci. U.S.A. 95 (14): 8175–80. Bibcode:1998PNAS...95.8175M. doi:10.1073/pnas.95.14.8175. PMC 20949. PMID 9653160.