NAT5

N-terminal acetyltransferase B complex catalytic subunit NAT5 is an enzyme that in humans is encoded by the NAT5 gene.[5][6]

NAA20
Identifiers
Aliases	NAA20, NAT3, NAT3P, NAT5, NAT5P, dJ1002M8.1, N(alpha)-acetyltransferase 20, NatB catalytic subunit, N-alpha-acetyltransferase 20, NatB catalytic subunit
External IDs	OMIM: 610833 MGI: 1915127 HomoloGene: 7165 GeneCards: NAA20
Gene location (Human) Chr. Chromosome 20 (human)[1] Band 20p11.23 Start 20,017,310 bp[1] End 20,033,655 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2 G1|2 71.28 cM Start 145,902,099 bp[2] End 145,916,425 bp[2]
Gene ontology Molecular function • transferase activity • transferase activity, transferring acyl groups • peptide alpha-N-acetyltransferase activity Cellular component • intracellular • NatB complex • cytosol • cell nucleus • cytoplasm Biological process • N-terminal peptidyl-methionine acetylation Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	51126	67877
Ensembl	ENSG00000173418	ENSMUSG00000002728
UniProt	P61599	P61600
RefSeq (mRNA)	NM_181528 NM_016100 NM_181527	NM_001141965 NM_026425
RefSeq (protein)	NP_057184 NP_852668 NP_852669	NP_001135437 NP_080701
Location (UCSC)	Chr 20: 20.02 – 20.03 Mb	Chr 2: 145.9 – 145.92 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000173418 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000002728 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Sugiura N, Adams SM, Corriveau RA (Oct 2003). "An evolutionarily conserved N-terminal acetyltransferase complex associated with neuronal development". J Biol Chem. 278 (41): 40113–20. doi:10.1074/jbc.M301218200. PMID 12888564.
6. "Entrez Gene: NAT5 N-acetyltransferase 5".

Further reading

• Vitale N, Pacheco-Rodriguez G, Ferrans VJ, et al. (2000). "Specific functional interaction of human cytohesin-1 and ADP-ribosylation factor domain protein (ARD1)". J. Biol. Chem. 275 (28): 21331–9. doi:10.1074/jbc.M909642199. PMID 10748148.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
• Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. doi:10.1038/414865a. PMID 11780052.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Polevoda B, Cardillo TS, Doyle TC, et al. (2003). "Nat3p and Mdm20p are required for function of yeast NatB Nalpha-terminal acetyltransferase and of actin and tropomyosin". J. Biol. Chem. 278 (33): 30686–97. doi:10.1074/jbc.M304690200. PMID 12783868.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
• Arnesen T, Anderson D, Torsvik J, et al. (2006). "Cloning and characterization of hNAT5/hSAN: an evolutionarily conserved component of the NatA protein N-alpha-acetyltransferase complex". Gene. 371 (2): 291–5. doi:10.1016/j.gene.2005.12.008. PMID 16507339.
• Sánchez-Puig N, Fersht AR (2006). "Characterization of the native and fibrillar conformation of the human Nα-acetyltransferase ARD1". Protein Sci. 15 (8): 1968–76. doi:10.1110/ps.062264006. PMC 2242591. PMID 16823041.