BTBD14B

Nucleus accumbens-associated protein 1 is a protein that in humans is encoded by the NACC1 gene.[5][6]

NACC1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3GA1, 4U2N
Identifiers
Aliases	NACC1, BEND8, BTBD14B, BTBD30, NAC-1, NAC1, nucleus accumbens associated 1, NECFM
External IDs	OMIM: 610672 MGI: 1914080 HomoloGene: 12042 GeneCards: NACC1
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19p13.13 Start 13,116,862 bp[1] End 13,141,147 bp[1]
Gene location (Mouse) Chr. Chromosome 8 (mouse)[2] Band 8 C2|8 41.02 cM Start 84,670,479 bp[2] End 84,687,902 bp[2]
RNA expression pattern More reference expression data
Orthologs
Species	Human	Mouse
Entrez	112939	66830
Ensembl	ENSG00000160877	ENSMUSG00000001910
UniProt	Q96RE7	Q7TSZ8
RefSeq (mRNA)	NM_052876	NM_025788
RefSeq (protein)	NP_443108	NP_080064
Location (UCSC)	Chr 19: 13.12 – 13.14 Mb	Chr 8: 84.67 – 84.69 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000160877 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000001910 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Strausberg RL, Feingold EA, Grouse LH, et al. (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
6. "Entrez Gene: BTBD14B BTB (POZ) domain containing 14B".

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External links

• Human NACC1 genome location and NACC1 gene details page in the UCSC Genome Browser.
• PDBe-KB provides an overview of all the structure information available in the PDB for Human Nucleus accumbens-associated protein 1 (BTBD14B)

Further reading

• Nakayama K, Nakayama N, Wang TL, Shih IeM (2007). "NAC-1 controls cell growth and survival by repressing transcription of Gadd45GIP1, a candidate tumor suppressor". Cancer Res. 67 (17): 8058–64. doi:10.1158/0008-5472.CAN-07-1357. PMID 17804717.
• Davidson B, Berner A, Trope' CG, et al. (2007). "Expression and clinical role of the bric-a-brac tramtrack broad complex/poxvirus and zinc protein NAC-1 in ovarian carcinoma effusions". Hum. Pathol. 38 (7): 1030–6. doi:10.1016/j.humpath.2006.12.009. PMID 17391728.
• Nakayama K, Nakayama N, Davidson B, et al. (2007). "A BTB/POZ protein, NAC-1, is related to tumor recurrence and is essential for tumor growth and survival". Proc. Natl. Acad. Sci. U.S.A. 103 (49): 18739–44. doi:10.1073/pnas.0604083103. PMC 1693732. PMID 17130457.
• Korutla L, Wang PJ, Mackler SA (2005). "The POZ/BTB protein NAC1 interacts with two different histone deacetylases in neuronal-like cultures". J. Neurochem. 94 (3): 786–93. doi:10.1111/j.1471-4159.2005.03206.x. PMID 16033423.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Korutla L, Wang PJ, Lewis DM, et al. (2002). "Differences in expression, actions and cocaine regulation of two isoforms for the brain transcriptional regulator NAC1". Neuroscience. 110 (3): 421–9. doi:10.1016/S0306-4522(01)00518-8. PMID 11906783.