MTPN

Myotrophin is a protein that in humans is encoded by the MTPN gene.[5][6]

MTPN
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesMTPN, GCDP, V-1, myotrophin
External IDsOMIM: 606484 MGI: 99445 HomoloGene: 40607 GeneCards: MTPN
Gene location (Human)
Chr.Chromosome 7 (human)[1]
Band7q33Start135,926,760 bp[1]
End135,977,359 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

136319

14489

Ensembl

ENSG00000105887

ENSMUSG00000029840

UniProt

P58546

P62774

RefSeq (mRNA)

NM_145808

NM_008098

RefSeq (protein)

NP_665807

NP_032124

Location (UCSC)Chr 7: 135.93 – 135.98 MbChr 6: 35.51 – 35.54 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

MTPN has been shown to interact with RELA[7] and REL.[7]

gollark: Because YAML tries to look "simple", it's actually wildly complex, problem-prone, and has weird quirks. Like Go, sort of.
gollark: TOML is, in my opinion, nicer for configs. It's basically standardized INI.
gollark: Also, possibly partly due to point 3, many (dynamic) languages actually implement YAML parsing in a way which allows arbitrary code execution by default. I think Python's yaml library does it unsafely by default (EDIT: see here: https://www.arp242.net/yaml-config.html though PyYaml at least appears to be changing this now).
gollark: It's not simple. The standard is extremely complex and there are something like nine ways to do multiline strings.
gollark: You might need to enable WAL mode.

References

  1. GRCh38: Ensembl release 89: ENSG00000105887 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000029840 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Mitra S, Timur AA, Gupta S, Wang Q, Sen S (July 2001). "Assignment of myotrophin to human chromosome band 7q33→q35 by in situ hybridization". Cytogenet Cell Genet. 93 (1–2): 151–2. doi:10.1159/000056974. PMID 11474205.
  6. "Entrez Gene: MTPN myotrophin".
  7. Knuefermann, Pascal; Chen Peter; Misra Arunima; Shi Shu-Ping; Abdellatif Maha; Sivasubramanian Natarajan (June 2002). "Myotrophin/V-1, a protein up-regulated in the failing human heart and in postnatal cerebellum, converts NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers". J. Biol. Chem. United States. 277 (26): 23888–97. doi:10.1074/jbc.M202937200. ISSN 0021-9258. PMID 11971907.

Further reading

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