Monalizumab
Monalizumab (formerly IPH2201) is an investigational drug being studied for rheumatoid arthritis, gynecologic malignancies[1] and other cancers.[2][3]
| Monoclonal antibody | |
|---|---|
| Type | ? |
| Source | Humanized |
| Target | NKG2A |
| Legal status | |
| Legal status |
|
| Identifiers | |
| CAS Number | |
| ChemSpider |
|
| UNII | |
Mechanism of action
Monalizumab is a monoclonal antibody targeted at NKG2A.[4] It is a checkpoint inhibitor.[5]
gollark: Why.
gollark: Guess they're Ale!
gollark: "Ale"? Interesting.
gollark: Theory: all Krist addresses are now controlled by Terrariola.
gollark: This is why we should have 1024-bit Krist addresses.
References
- A Dose-Ranging Study of IPH2201 in Patients With Gynecologic Malignancies
- IPH2201 studies
- First Clinical Data For Monalizumab As A Single Agent In Cancer Patients Show Favorable Safety Profile
- AstraZeneca Inks $1.8B in Immuno-Oncology Deals as Q1 Profit Dips
- "monalizumab". Archived from the original on 2016-12-20. Retrieved 2016-12-09.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.