Michel Bouvier

Michel Bouvier (born September 14, 1958) is a Canadian biochemist and molecular pharmacologist. He is a professor of biochemistry and molecular medicine at Université de Montréal; a principal investigator and the Chief Executive Officer at the Institute for Research in Immunology and Cancer; and an Associate Vice-President in Research, Scientific Discovery, Creation and Innovation at Université de Montréal. His work focuses on the study of cell signaling towards the discovery of new pharmaceutical drugs.[3]

Michel Bouvier
Born (1958-09-14) September 14, 1958
CitizenshipCanadian
AwardsFellow of the Academy of Science of the Royal Society of Canada[1]/ Fellow of the Canadian Academy of Health Sciences / Canada Research Chair in Signal Transduction and Molecular Pharmacology[2]
Scientific career
FieldsBiochemistry and molecular pharmacology

Biography

Michel Bouvier earned a B.Sc. in Biochemistry (1979) and a Ph.D. in Neurological Sciences (1985) from Université de Montréal, and then completed a post-doctoral fellow (1985-1989) at Duke University under the supervision of Dr. Robert J. Lefkowitz (2012 Nobel Prize in Chemistry[4]). Bouvier is a professor in the Department of Biochemistry and Molecular Medicine at the Faculty of Medicine of Université de Montréal and a principal investigator at the Institute for Research in Immunology and Cancer (IRIC) at Université de Montréal.[5]

Research

He is a world-known expert[6][7] in cell signaling and drug discovery, notably in the field of G protein-coupled receptors (GPCRs).[8] GPCRs constitute the largest single protein family involved in the transduction of hormonal signals and neurotransmitters. Their physiological significance makes them a prime target in drug development, and over a third of existing drugs use GPCRs as their target site of action. Bouvier’s work in the regulation of receptors led to new paradigms (inverse agonism; pharmacological chaperones; receptor polymerization; and pluri-dimensionality of signaling), which, coupled with the development of bioluminescence resonance energy transfer (BRET)-based methods, have a direct impact on drug discovery.[9] He has authored over 260 scientific articles,[10] filed 36 patent applications, and delivered over 400 lectures as a guest lecturer. Bouvier holds the Canada Research Chair in Signal Transduction and Molecular Pharmacology[11]

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gollark: Loops are !!IMPERATIVE!!, map is glorious functional purity.
gollark: No, small. Anyway, the weird format string/lambda/map oneliner is much clearer than a loop.
gollark: No use using two lines when one works, my monitor isn't that small.

References
  1. Michel Bouvier at RSC
  2. Research Chair
  3. "Department of Biochemistry and Molecular Medicine, Faculty of Medicine, Université de Montréal (French)". www.biochimie.umontreal.ca.
  4. "Michel Bouvier | FORCES magazine". www.magazineforces.com. Retrieved 1 March 2016.
  5. "Department of Biochemistry and Molecular Medicine, Faculty of Medicine, Université de Montréal (French)". www.biochimie.umontreal.ca. Retrieved 2016-03-01.
  6. "The World's Most Influential Scientific Minds 2014" (PDF). Retrieved 1 March 2016.
  7. User, Super. "Domain Therapeutics, Université de Montréal, IRICoR and McGill University sign new licensing and partnership agreement on G-Protein Coupled Receptor biosensor technology". Parc d'Innovation de Strasbourg | Eco-parc d'activité en Alsace. Retrieved 2016-03-01.
  8. "Université de Montréal (via noodls) / Michel Bouvier at the helm of IRIC". www.noodls.com. Retrieved 2016-03-01.
  9. "MICHEL BOUVIER – Canadian Academy of Health Sciences / Académie canadianne des sciences de la santé". cahs-acss.ca. Retrieved 2016-03-01.
  10. "Michel Bouvier". ResearchGate. Retrieved 2016-03-01.
  11. Government of Canada, Industry Canada (2012-11-29). "Canada Research Chairs". Retrieved 2016-03-01.
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