Mfsd5

Major facilitator superfamily domain containing 5 (MFSD5, hsMOT) is an atypical SLC expressed in neuronal plasma membranse.[1] It is a plausible Solute carrier transporter.[2] It transports molybdate anions,[3] and it interacts with GLP-1R.[4]

HGNC:28156

MFSD5 belongs to AMTF6.[5]

References

Perland, Emelie; Lekholm, Emilia; Eriksson, Mikaela M.; Bagchi, Sonchita; Arapi, Vasiliki; Fredriksson, Robert (2016). "The Putative SLC Transporters Mfsd5 and Mfsd11 Are Abundantly Expressed in the Mouse Brain and Have a Potential Role in Energy Homeostasis". PLOS ONE. 11 (6): e0156912. doi:10.1371/journal.pone.0156912. ISSN 1932-6203. PMC 4896477. PMID 27272503.
Perland, Emelie; Fredriksson, Robert (March 2017). "Classification Systems of Secondary Active Transporters". Trends in Pharmacological Sciences. 38 (3): 305–315. doi:10.1016/j.tips.2016.11.008. ISSN 1873-3735. PMID 27939446.
Tejada-Jiménez, Manuel; Galván, Aurora; Fernández, Emilio (2011-04-19). "Algae and humans share a molybdate transporter". Proceedings of the National Academy of Sciences of the United States of America. 108 (16): 6420–6425. doi:10.1073/pnas.1100700108. ISSN 1091-6490. PMC 3080982. PMID 21464289.
Huang, X.; Dai, F. F.; Gaisano, G.; Giglou, K.; Han, J.; Zhang, M.; Kittanakom, S.; Wong, V.; Wei, L. (September 2013). "The identification of novel proteins that interact with the GLP-1 receptor and restrain its activity". Molecular Endocrinology (Baltimore, Md.). 27 (9): 1550–1563. doi:10.1210/me.2013-1047. ISSN 1944-9917. PMC 5415235. PMID 23864651.
Perland, Emelie; Bagchi, Sonchita; Klaesson, Axel; Fredriksson, Robert (2017-09-01). "Characteristics of 29 novel atypical solute carriers of major facilitator superfamily type: evolutionary conservation, predicted structure and neuronal co-expression". Open Biology. 7 (9): 170142. doi:10.1098/rsob.170142. ISSN 2046-2441. PMC 5627054. PMID 28878041.

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[1] Perland, Emelie; Lekholm, Emilia; Eriksson, Mikaela M.; Bagchi, Sonchita; Arapi, Vasiliki; Fredriksson, Robert (2016). "The Putative SLC Transporters Mfsd5 and Mfsd11 Are Abundantly Expressed in the Mouse Brain and Have a Potential Role in Energy Homeostasis". PLOS ONE. 11 (6): e0156912. doi:10.1371/journal.pone.0156912. ISSN 1932-6203. PMC 4896477. PMID 27272503.

[2] Perland, Emelie; Fredriksson, Robert (March 2017). "Classification Systems of Secondary Active Transporters". Trends in Pharmacological Sciences. 38 (3): 305–315. doi:10.1016/j.tips.2016.11.008. ISSN 1873-3735. PMID 27939446.

[3] Tejada-Jiménez, Manuel; Galván, Aurora; Fernández, Emilio (2011-04-19). "Algae and humans share a molybdate transporter". Proceedings of the National Academy of Sciences of the United States of America. 108 (16): 6420–6425. doi:10.1073/pnas.1100700108. ISSN 1091-6490. PMC 3080982. PMID 21464289.

[4] Huang, X.; Dai, F. F.; Gaisano, G.; Giglou, K.; Han, J.; Zhang, M.; Kittanakom, S.; Wong, V.; Wei, L. (September 2013). "The identification of novel proteins that interact with the GLP-1 receptor and restrain its activity". Molecular Endocrinology (Baltimore, Md.). 27 (9): 1550–1563. doi:10.1210/me.2013-1047. ISSN 1944-9917. PMC 5415235. PMID 23864651.

[5] Perland, Emelie; Bagchi, Sonchita; Klaesson, Axel; Fredriksson, Robert (2017-09-01). "Characteristics of 29 novel atypical solute carriers of major facilitator superfamily type: evolutionary conservation, predicted structure and neuronal co-expression". Open Biology. 7 (9): 170142. doi:10.1098/rsob.170142. ISSN 2046-2441. PMC 5627054. PMID 28878041.