Metal-binding protein

Metal-binding proteins are proteins or Protein domains that chelate a metal ion.[1]

In some cases this is a necessary part of their folding and maintenance of a tertiary structure. Alternatively, a metal-binding protein may maintain its structure without the metal (apo form) and bind it as a ligand (e.g. as part of metal homeostasis). In other cases a coordinated metal cofactor is used in the active site of an enzyme to assist catalysis.

References

  1. Berg, J. M. (1990-04-25). "Zinc fingers and other metal-binding domains. Elements for interactions between macromolecules". The Journal of Biological Chemistry. 265 (12): 6513–6516. ISSN 0021-9258. PMID 2108957.
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