Merbecovirus
Merbecovirus is a subgenus of viruses in the genus Betacoronavirus.[1] The viruses in this subgenus were previously known as group 2c coronaviruses.[2][3]
| Merbecovirus | |
|---|---|
 | |
| MERS-CoV particles as seen by negative stain electron microscopy. Virions contain characteristic club-like projections emanating from the viral membrane. | |
Virus classification  | |
| (unranked): | Virus |
| Realm: | Riboviria |
| Kingdom: | Orthornavirae |
| Phylum: | Pisuviricota |
| Class: | Pisoniviricetes |
| Order: | Nidovirales |
| Family: | Coronaviridae |
| Genus: | Betacoronavirus |
| Subgenus: | Merbecovirus |
| Species[1] | |
| |
Structure
The viruses of this subgenus, like other coronaviruses, have a lipid bilayer envelope in which the membrane (M), envelope (E) and spike (S) structural proteins are anchored.[4][5]
gollark: I am generally against imposing regulation on *deterministic* things, so no.
gollark: I am generally against imposing regulation on random things, so no.
gollark: As I said, I hackerized it.
gollark: I managed to connect PotatOS directly to Discord and hackerize it.
gollark: this message I also
See also
- Embecovirus (group 2a)
- Sarbecovirus (group 2b)
- Nobecovirus (group 2d)
References
- "Virus Taxonomy: 2018 Release". International Committee on Taxonomy of Viruses (ICTV). October 2018. Retrieved 24 January 2019.
- Woo, Patrick C. Y.; Wang, Ming; Lau, Susanna K. P.; Xu, Huifang; Poon, Rosana W. S.; Guo, Rongtong; Wong, Beatrice H. L.; Gao, Kai; Tsoi, Hoi-wah; Huang, Yi; Li, Kenneth S. M. (February 2007). "Comparative Analysis of Twelve Genomes of Three Novel Group 2c and Group 2d Coronaviruses Reveals Unique Group and Subgroup Features". Journal of Virology. 81 (4): 1574–1585. doi:10.1128/JVI.02182-06. ISSN 0022-538X. PMC 1797546. PMID 17121802.
See figure 2.
- Wong, Antonio C. P.; Li, Xin; Lau, Susanna K. P.; Woo, Patrick C. Y. (2019-02-20). "Global Epidemiology of Bat Coronaviruses". Viruses. 11 (2): 174. doi:10.3390/v11020174. ISSN 1999-4915. PMC 6409556. PMID 30791586.
CoVs are classified into four genera, Alphacoronavirus, Betacoronavirus, Gammacoronavirus and Deltacoronavirus. Within Betacoronavirus, they can be further subclassified into lineages A, B, C and D [1]. In 2018, these four lineages were reclassified as subgenera of Betacoronavirus, and renamed as Embecovirus (previous lineage A), Sarbecovirus (previous lineage B), Merbecovirus (previous lineage C) and Nobecovirus (previous lineage D) [2]. In addition, a fifth subgenus, Hibecovirus, was also included (Figure 1) [2].
- Lai, Michael M. C.; Cavanagh, David (1997-01-01), Maramorosch, Karl; Murphy, Frederick A.; Shatkin, Aaron J. (eds.), "The Molecular Biology of Coronaviruses; III. Structure of Virions; A. Virion Morphology", Advances in Virus Research, Academic Press, 48, pp. 5–6, retrieved 2020-02-28
- Woo, Patrick C. Y.; Huang, Yi; Lau, Susanna K. P.; Yuen, Kwok-Yung (2010-08-24). "Coronavirus Genomics and Bioinformatics Analysis". Viruses. 2 (8): 1804–1820. doi:10.3390/v2081803. ISSN 1999-4915. PMC 3185738. PMID 21994708.
The presence of HE genes exclusively in members of Betacoronavirus subgroup A, but not members of Betacoronavirus subgroup B, C and D suggested that the recombination had probably occurred in the ancestor of members of Betacoronavirus subgroup A, after diverging from the ancestor of other subgroups of Betacoronavirus.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.