Mamun Al Mahtab (Shwapnil)

Mamun Al Mahtab (Shwapnil) is a Bangladeshi hepatologist.

Mamun Al Mahtab (Shwapnil)
Al Mahtab in 2019
Born (1970-08-22) August 22, 1970
Bangladesh
OccupationChairman, Department of Hepatology, Bangabandhu Sheikh Mujib Medical University (BSMMU)
Spouse(s)Dr. Nuzhat Choudhury
Children2
Parent(s)
  • late Mahtab Uddin Ahmed
  • Ayesha Mahtab

Early life and education

He spent his early life in Dhaka. His schooling started in Rosy Ann Centre, an English medium kindergarten. He subsequently switched to Banani Bidyaniketan and passed Secondary School Certificate examination in 1985 with star marks. He completed Higher Secondary Certificate from Dhaka College in 1987 also with star marks.

He then moved to Mymensingh where he was admitted to the Mymensingh Medical College for his undergraduate medical studies. He got involved in student politics of Bangladesh Chatra League there, inspired by the ideals of Father of the Nation Bangabandhu Sheikh Mujibur Rahman. He was a member of the Central Committee (i.e. Mainuddin Hassan Choudhury - Iqbalur Rahim - Mahbububul Haque Shakil committee) of the organization.

Professor Mahtab graduated from Mymensingh Medical College in 1995. He gained an MSc in Gastroenterology from the University of London in 1998 and subsequently did an MD in Hepatology at Bangabandhu Sheikh Mujib Medical University in 2006.[1] He is Fellow of the Royal College of Physicians of London, the Royal College of Physicians of Ireland, the Indian College of Physicians and the American College of Gastroenterology.

Career

Mahtab is currently working as Chairman, Department of Hepatology, Bangabandhu Sheikh Mujib Medical University (BSMMU).[2] He is also a Visiting Professor at the Department of Gastroenterology & Metabology, Ehime University, Japan.

He is involved with teaching of post-graduate students and supervision of MD (Hepatology) thesis under BSMMU. He is PhD thesis co-supervisor and PhD examiner of the University of Malaya, Malaysia, Tehran University, Iran, University of Madras and Dr. A P J Abul Kalam Technical University, India and University of Dhaka and Rajshahi University in Bangladesh.

Research

He has conducted several clinical trials, which have been presented at international conferences and published in peer-reviewed journals.[3][4][5][6][6][7][8][9][10][11][12][13][14][15][16][17][18][18][19][20][21][22][23][24][25][26] He is the Principal Investigator of the Phase-I/II and III clinical trials of NASVAC,[5][27][28] a new generic for chronic hepatitis B, which is already registered in Bangladesh, Cuba, Nicaragua, Ecuador, Belarus and Angola. It is the first drug to be developed and registered in Bangladesh. NASVAC is also the ‘first novel molecule’ to be registered by the Directorate General of Drug Administration of the Bangladesh Government.

Publications

Mahtab has compiled six books, namely ‘Liver: A Complete Book on Hepato-Pancreato-Biliary Diseases’, published by Elsevier (2009),[29] ’Comprehensive Text Book on Hepatitis B’, published by Jaypee (2010),[30] ‘Fatty Liver Disease’ (2012) and 'Hepatitis Management Update' (2015) published by McMillan and 'Text Book of Hepato-Gastroenterology' (2015)[31] and 'Practical Hepato-Gastroenterology Prescriber' (2016) published by Jaypee.[32]

He has more than 200 scientific publications, more than 300 conference abstracts and over 200 international and national conference talks to his credit.

He has published Bengali translations of 'White House Years: The Tilt-The India-Pakistan Crisis of 1971' by Dr. Henry Kissinger and 'Victory in Bangladesh' by Major General (Retd.) Lachman Singh.[33] He contributes articles on socio-political and health related issues regularly to mainstream newspapers and online news portals of Bangladesh. He has recently published three Bengali books, namely ‘Shekal Ekaler Korcha’[34] ‘Ekhon Shomoy Bangladesher’[35] from Mawla Brothers and ‘Liver Chikitshae Notun Sombhabona’[36] from Mutkodhara, which are leading publication houses of the country. He is a Life Member of Bangla Academy.

Mahtab is serving on the Editorial Boards of several international journals in the fields of Hepatology and Gastroenterology including, Hepatology Internaional (journal of Asian Pacific Association for the Study of the Liver), Euroasian Journal of Hepato-Gastroenterology (Journal of Euroasian Gastroenterological Association) and Journal of Clinical and Experimental Hepatology (journal of Indian Association for the Study of the Liver).

Awards

He has received awards for scientific works from different major international bodies including the American Association for the Study of Liver Diseases (AASLD), World Gastroenterology Organization (WGO), Asian Pacific Association for the Study of the Liver (APASL), International Association for the Study of the Liver (IASL), Euroasian Gastroenterological Association (EGA), Japan Society of Hepatology (JSH), Indian National Association for the Study of the Liver (INASL), Turkish Hepato-Biliary-Pancreatology Association (HEBIPA) and Asia-Pacific Primary Liver Cancer Expert (APPLE) Association.

He received the “Order of Merit” from Euroasian Gastroenterological Association in 2014, "Blumberg Oration 2015" conferred by Kalinga Gastroenterology Foundation, India, "Distinguished Scientist (Hepatology) Award" from Venus Research Foundation, India in 2016, “Albert Nelson Marquis Life Time Achievement Award 2018” from Marquis Who's Who and “Bishuddhananda Gold Medal” from Bangladesh Bouddha Krishty Prochar Songho in 2018. His name has been included in “Marquis Who’s Who of the World 2017”.[37]

Organizational affiliations

He is four times elected Secretary General of Association for the Study of the Liver Diseases Bangladesh (ASLDB) (the national Hepatology Association of Bangladesh).[38] He is also founder President of Bangabandhu Sheikh Mujib Medical University Hepatology Alumni Association[39] and Executive Chairman of Forum for the Study of the Liver Bangladesh.[40]

He is the founder General Secretary of Bangladesh Stem Cell and Regenerative Medicine Society.[41]

He has to his credit organizing several ‘first time in Bangladesh’ medical conferences including the first STEMCON in 2017 (1st international conference on stem cell therapy in Bangladesh) and first EndoVasculoCon in 2019 (1st live conference from endoscopy suit and vascular lab in the region).[42]

Recently Professor Mahtab played key role in organizing the First Padma-Ganga-Gomti Liver Conference 2019 at Bangabandhu Sheikh Mujib Medical University in Dhaka. This is the first ever scientific conference of only Bengali Hepatologists. The conference was jointly organized by Forum for the Study of the Liver Bangladesh, Liver Foundation West Bengal and Hepatitis Foundation of Tripura. It was organized as a token of respect of the Bengali Hepatologists to Bangabandhu Sheikh Mujibur Rahman, Father of the Nation of Bangladesh and the greatest Bengali of a thousand years on the occasion of his birth centennial. The second and third conferences will be organized in Shantiniketon and Agartala in March and August 2020 respectively.[43]

Mahtab is the Vice President of Euroasian Gastroenterological Association,[44] Secretary General of South Asian Association for the Study of the Liver (SAASL)[45] and International Coordinator of Indian National Association for the Study of the Liver (INASL).[46]

Mahtab is member of the APASL Working Parties on hepatitis B, Hepatitis C, acute on chronic liver failure (ACLF) and liver fibrosis. He is a member of the Steering Committee of the Patient Registry of Hepatitis Free Pahang Society, Malaysia.

He is only Bangladeshi Hepatologists among the 150 eminent Hepatologists from all over the globe, who proclaimed June 12 as ‘International NASH Day’ through a joint deceleration released simultaneously from London, Paris and New York in 2018.

He is Member Secretary of Sampritee Bangladesh, Secretary General of Bangladesh Study Trust, Treasurer of Forum for Secular Bangladesh and Executive Member of Dhaka City North Awami League.

Personal life

Mahtab comes from Sylhet. He is married to Dr. Nuzhat Choudhury.[47][48] They have two children. His father late Mahtab Uddin Ahmed was an eminent civil engineer of Bangladesh. He served the Government of Bangladesh in the capacity of Chief Engineer, Roads & Highways Department. His mother Mrs. Ayesha Mahtab[49] is a house wife.

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References
  1. "BSMMU-Hepatology Dept".
  2. "Faculty of Hepatology of BSMMU". BSMMU.
  3. Al-Mahtab, Mamun; Bazinet, Michel; Vaillant, Andrew (2016). "Safety and Efficacy of Nucleic Acid Polymers in Monotherapy and Combined with Immunotherapy in Treatment-Naive Bangladeshi Patients with HBeAg+ Chronic Hepatitis B Infection". PLOS ONE. 11 (6): e0156667. Bibcode:2016PLoSO..1156667A. doi:10.1371/journal.pone.0156667. PMC 4892580. PMID 27257978.
  4. Raihan, Ruksana; Akbar, Sheikh Mohammad Fazle; Al Mahtab, Mamun; Takahashi, Kazuaki; Masumoto, Junya; Tabassum, Shahina; Tee, Kok Keng; Binti Mohamed, Rosmawati (2019). "Genomic analysis of Hepatitis B virus and its association with disease manifestations in Bangladesh". PLOS ONE. 14 (6): e0218744. Bibcode:2019PLoSO..1418744R. doi:10.1371/journal.pone.0218744. PMID 31251754.
  5. Al Mahtab, Mamun; Akbar, Sheikh Mohammad Fazle; Aguilar, Julio Cesar; Guillen, Gerardo; Penton, Euduaro; Tuero, Angela; Yoshida, Osamu; Hiasa, Yoichi; Onji, Morikazu (2018). "Treatment of chronic hepatitis B naïve patients with a therapeutic vaccine containing HBs and HBc antigens (a randomized, open and treatment controlled phase III clinical trial)". PLOS ONE. 13 (8): e0201236. Bibcode:2018PLoSO..1301236A. doi:10.1371/journal.pone.0201236. PMID 30133478.
  6. Stefanska, Barbara; Bouzelmat, Aurelie; Huang, Jian; Suderman, Matthew; Hallett, Michael; Han, Ze-Guang; Al-Mahtab, Mamun; Akbar, Sheikh Mohammad Fazle; Khan, Wasif Ali; Raqib, Rubhana; Szyf, Moshe (2013). "Discovery and Validation of DNA Hypomethylation Biomarkers for Liver Cancer Using HRM-Specific Probes". PLOS ONE. 8 (8): e68439. Bibcode:2013PLoSO...868439S. doi:10.1371/journal.pone.0068439.
  7. Wait, S.; Kell, E.; Hamid, S.; Muljono, D. H.; Sollano, J.; Mohamed, R.; Shah, S.; Abbas, Z.; Johnston, J.; Tanwandee, T.; Wallace, J. (2016). "Hepatitis B and hepatitis C in southeast and southern Asia: challenges for governments". The Lancet. Gastroenterology & Hepatology. 1 (3): 248–255. doi:10.1016/S2468-1253(16)30031-0. PMID 28404097.
  8. Al-Mahtab, Mamun; Akbar, Sheikh Mohammad Fazle; Garg, Hitendra (2016). "Influence of variceal bleeding on natural history of ACLF and management options". Hepatology International. 10 (3): 436–439. doi:10.1007/s12072-015-9677-2. PMID 26589951.
  9. Saha, Biplob Kumar; Mahtab, Mamun Al; Akbar, Sheikh Mohammad Fazle; Noor-e-Alam, Sheikh Mohammad; Mamun, Ayub Al; Hossain, Sharker Mohammad Shahadat; Alam, Mohammad Ashraful; Moben, Ahmed Lutful; Khondaker, Faiz Ahmad; Chowdhury, Forhadul Islam; Raihan, Ruksana; Rahman, Salimur; Choudhury, Ashok Kumar (2017). "Therapeutic implications of granulocyte colony stimulating factor in patients with acute-on-chronic liver failure: increased survival and containment of liver damage". Hepatology International. 11 (6): 540–546. doi:10.1007/s12072-017-9814-1. PMID 28840583.
  10. Al-Mahtab, Mamun; Akbar, Sheikh Mohammad Fazle; Aguilar, Julio Cesar; Uddin, Md. Helal; Khan, Md. Sakirul Islam; Rahman, Salimur (2013). "Therapeutic potential of a combined hepatitis B virus surface and core antigen vaccine in patients with chronic hepatitis B". Hepatology International. 7 (4): 981–989. doi:10.1007/s12072-013-9486-4.
  11. "Assessment of Clinical Utility of Low and High Normal Alanine Aminotransferase Values in Patients with Chronic Hepatitis B Virus Infection in Bangladesh". KARGER.
  12. "Biochemical, Virological, Immunological and Histopathological Features of 702 Incidentally Detected Chronic Hepatitis B Virus Carriers in Bangladesh". KARGER.
  13. Chavarria, L.; Cordoba, J.; Rahman, Salimur (2015). "Favorable Genotype is Predominant at IL28B rs12979860 Polymophism in Apparent Healthy Bangladeshi Population". Journal of Clinical and Experimental Hepatology. 5 (Suppl 1): S69-74. doi:10.1016/j.jceh.2013.10.001. PMC 4442861. PMID 26041961.
  14. Abedin, Mohammed Forhad; Al Mahtab, Mamun; Rahman, Salimur; Ahmad, Nooruddin (2015). "Minimal Hepatic Encephalopathy is an Under Recognized Entity in Clinical Practice of Bangladeshi Physician". Journal of Clinical and Experimental Hepatology. 5: S30. doi:10.1016/j.jceh.2015.07.211.
  15. Abedin, Mohammed Forhad; Mahtab, Mamun Al; Akbar, Sheikh Mohammad Fazle; Ahmad, Nooruddin (2017). "Minimal Hepatic Encephalopathy Is An Under Recognized Entity in Clinical Practice Of Bangladeshi Physicians". Journal of Clinical and Experimental Hepatology. 7: S76. doi:10.1016/j.jceh.2017.01.102.
  16. Karim, Md. F.; Podder, Provat K.; Islam, Md. N.; Ahmed, Faroque; Al-Mahtab, Mamun; Rahman, Salimur (2017). "Is Fibroscan a Substitute to Ultrasound in Prdicting Liver Fibrosis?". Journal of Clinical and Experimental Hepatology. 7: S101. doi:10.1016/j.jceh.2017.05.181.
  17. Malakar, Debraj; Al-Mahtab, Mamun; Noor-e-Alam, Sheikh M.; Manik, Abul H.; Masum, Abdullah A.; Mamun, Ayub A.; Rahman, Salimur (2017). "Comparative Study of Treatment Outcome With Tenofovir and Telbivudine in Patients With Hepatitis B Related Acute on Chronic Liver Failure". Journal of Clinical and Experimental Hepatology. 7: S118. doi:10.1016/j.jceh.2017.05.211.
  18. Mamun-Al-Mahtab; Karim, Fazal; Foster, Graham; Akbar, SM Fazle; Rahman, Salimur (2011). "Prevalence and Risk Factors of Asymptomatic Hepatitis C Virus Infection in Bangladesh". Journal of Clinical and Experimental Hepatology. 1: 13–16. doi:10.1016/S0973-6883(11)60111-4. PMC 3940088. PMID 25755305.
  19. Moben, Ahmed Lutful; Noor-e-Alam, Mohammad; Rahim, M.A.; Khondoker, Faiz Ahmad; Majid, Farjana; Mahtab, Mamun Al (2016). "Prediction of Hepatic Encephalopathy by Liver Stiffness Measurement with Fibroscan in Patients with Cirrhosis of Liver". Journal of Clinical and Experimental Hepatology. 6: S56. doi:10.1016/j.jceh.2016.06.180.
  20. "Therapeutic application of HBV antigens to control HBV replication and prevent liver damage". jcehepatology.
  21. Rashid, Mohd Harun Or; Rashid, Humaira; Rashid, Tasnova; Rahman, Khalilur; Khan, Mahbubur Rahman; Hasan, Alaksar Sazid; Mahtab, Mamun Al (2018). "16. Study on recurrence of HCV infection after recommended treatment in a tertiary level hospital in Bangladesh". Journal of Clinical and Experimental Hepatology. 8: S20. doi:10.1016/j.jceh.2018.06.307.
  22. Rashid, Mohd Harun Or; Rahman, Md Khalilur; Khan, Mahbubur Rahman; Mahtab, Mamun Al; Hasan, Md Nahid; Rashid, Humaira; Hasan, Alaksar Sazid; Alim, Abdul (2018). "3. Study on lipid profile among adults with HBV and HCV related chronic liver diseases in Bangladesh-report from a tertiary centre". Journal of Clinical and Experimental Hepatology. 8: S51–S52. doi:10.1016/j.jceh.2018.06.364.
  23. "Designing Immune Therapy for Chronic Hepatitis B". jcehepatology.
  24. Omata, Masao; Kanda, Tatsuo; Wei, Lai; Yu, Ming-Lung; Chuang, Wang-Long; Ibrahim, Alaaeldin; Lesmana, Cosmas Rinaldi Adithya; Sollano, Jose; Kumar, Manoj; Jindal, Ankur; Sharma, Barjesh Chander; Hamid, Saeed S.; Dokmeci, A. Kadir; Al-Mahtab, Mamun; McCaughan, Geofferey W.; Wasim, Jafri; Crawford, Darrell H. G.; Kao, Jia-Horng; Yokosuka, Osamu; Lau, George K. K.; Sarin, Shiv Kumar (2016). "APASL consensus statements and recommendations for hepatitis C prevention, epidemiology, and laboratory testing". Hepatology International. 10 (5): 681–701. doi:10.1007/s12072-016-9736-3. PMC 5003900. PMID 27229718.
  25. Al-Mahtab, Mamun; Rahman, Salimur; Akbar, Sheikh Mohammad Fazle; Kamal, Mohammad; Khan, Mohammad Sakirul Islam (2010). "Clinical use of liver biopsy for the diagnosis and management of inactive and asymptomatic hepatitis B virus carriers in Bangladesh". Journal of Medical Virology. 82 (8): 1350–1354. doi:10.1002/jmv.21830. PMID 20572087.
  26. "Clinical use of liver biopsy for the diagnosis and management of inactive and asymptomatic hepatitis B virus carriers in Bangladesh". semanticscholar. 2010.
  27. Al Mahtab, M.; Akbar, S. M.; Aguilar, J. C.; Guillen, G.; Penton, E.; Tuero, A.; Yoshida, O.; Hiasa, Y.; Onji, M. (2018). "Treatment of chronic hepatitis B naïve patients with a therapeutic vaccine containing HBs and HBc antigens (a randomized, open and treatment controlled phase III clinical trial)". PLOS ONE. 13 (8): e0201236. Bibcode:2018PLoSO..1301236A. doi:10.1371/journal.pone.0201236. PMC 6104936. PMID 30133478.
  28. "Bangladeshi researchers develop advanced drug for Hepatitis B". Dhaka Tribune. 2017-10-25.
  29. Liver: A Complete Book on Hepato-Pancreato-Biliary Diseases. India: Elsevier India. 2009. ISBN 9788131216743.
  30. "Comprehensive Textbook of Hepatitis B". jaypeebrothers.
  31. "Textbook of Hepato-gastroenterology". jaypeebrothers.
  32. "Practical Hepato-Gastroenterology Prescriber". jaypeebrothers.
  33. "OPINION". bdnews24. 2015-07-28.
  34. সেকাল একালের কড়চা (হার্ডকভার). rokomari.
  35. এখন-সময়-বাংলাদেশের-(হার্ডকভার). banglaboi.
  36. লিভার চিকিৎসায় নতুন সম্ভাবনা (হার্ডকভার). rokomari.
  37. "Dr. Mamun Al Mahtab | Affiliation at the time of the award". viraw.
  38. "Association for the Study of Liver Diseases Bangladesh". asldb.
  39. "Hepatology Alumni Association of BSMMU launched, Prof Swapnil president". bdnews24.
  40. "Forum for the Study of the Liver Bangladesh". liverforum.
  41. স্টেম সেল থেরাপি: সফল এক আবিষ্কার. sarabangla (in Bengali). 2017-12-26.
  42. ঢাকায় অনুষ্ঠিত হল বিশ্বের প্রথম এন্ডোভাস্কুলোকন সম্মেলন. khobor71 (in Bengali).
  43. বঙ্গবন্ধুর চেতনা ধারণ করে জাতির সেবায় আত্মনিয়োগ করুন. dailyjanakantha (in Bengali).
  44. "EUROASIAN GASTROENTEROLOGICAL ASSOCIATION". euroasiangastro.
  45. "THE EXECUTIVE COMMITTEE OF SAASL". saasl.
  46. "INASL International Coordinators (IIC)". inasl.
  47. ডা. নুজহাত চৌধুরী. bdnews24.com (Opinion) (in Bengali). 2013-03-26.
  48. শহীদ বুদ্ধিজীবী ডাঃ আলীম চৌধুরীর কন্যা ডা. নুজহাত চৌধুরী (in Bengali). Bangladesh Awami League – via YouTube.
  49. মা দিবসে অনন্য ১০ মাকে বিশেষ সম্মাননা. Prothom Alo (in Bengali).
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