MT1B

Metallothionein-1B is a protein that in humans is encoded by the MT1B gene.[3][4][5]

MT1B
Identifiers
Aliases	MT1B, MT1, MT1Q, MTP, metallothionein 1B, MT-IB, MT-1B
External IDs	OMIM: 156349 HomoloGene: 48385 GeneCards: MT1B
Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16q13 Start 56,651,886 bp[1] End 56,653,204 bp[1]
Gene ontology Molecular function • zinc ion binding • metal ion binding Cellular component • cytoplasm • perinuclear region of cytoplasm • cell nucleus Biological process • negative regulation of growth • cellular response to zinc ion • cellular zinc ion homeostasis • detoxification of copper ion • cellular response to cadmium ion • cellular response to copper ion Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	4490	n/a
Ensembl	ENSG00000169688	n/a
UniProt	P07438	n/a
RefSeq (mRNA)	NM_005947	n/a
RefSeq (protein)	NP_005938	n/a
Location (UCSC)	Chr 16: 56.65 – 56.65 Mb	n/a
PubMed search	[2]	n/a
Wikidata
View/Edit Human

References

1. GRCh38: Ensembl release 89: ENSG00000169688 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. Karin M, Eddy RL, Henry WM, Haley LL, Byers MG, Shows TB (Oct 1984). "Human metallothionein genes are clustered on chromosome 16". Proc Natl Acad Sci U S A. 81 (17): 5494–8. Bibcode:1984PNAS...81.5494K. doi:10.1073/pnas.81.17.5494. PMC 391732. PMID 6089206.
4. Heguy A, West A, Richards RI, Karin M (Dec 1986). "Structure and tissue-specific expression of the human metallothionein IB gene". Mol Cell Biol. 6 (6): 2149–57. doi:10.1128/MCB.6.6.2149. PMC 367755. PMID 3785191.
5. "Entrez Gene: MT1B metallothionein 1B".

Further reading

• Lederer CW, Torrisi A, Pantelidou M, et al. (2007). "Pathways and genes differentially expressed in the motor cortex of patients with sporadic amyotrophic lateral sclerosis". BMC Genomics. 8: 26. doi:10.1186/1471-2164-8-26. PMC 1796866. PMID 17244347.
• Sun NN, Fastje CD, Wong SS, et al. (2005). "Dose-dependent transcriptome changes by metal ores on a human acute lymphoblastic leukemia cell line". Toxicology and Industrial Health. 19 (7–10): 157–63. doi:10.1191/0748233703th185oa. PMID 15747776.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Izmailova E, Bertley FM, Huang Q, et al. (2003). "HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages". Nat. Med. 9 (2): 191–7. doi:10.1038/nm822. PMID 12539042.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• West AK, Stallings R, Hildebrand CE, et al. (1991). "Human metallothionein genes: structure of the functional locus at 16q13". Genomics. 8 (3): 513–8. doi:10.1016/0888-7543(90)90038-V. PMID 2286373.