MRFAP1

MORF4 family-associated protein 1 is a protein that in humans is encoded by the MRFAP1 gene.[5][6]

MRFAP1
Identifiers
AliasesMRFAP1, PAM14, PGR1, Morf4 family associated protein 1, PGR1`
External IDsOMIM: 616905 MGI: 1914818 HomoloGene: 128357 GeneCards: MRFAP1
Gene location (Human)
Chr.Chromosome 4 (human)[1]
Band4p16.1Start6,640,091 bp[1]
End6,642,745 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

93621

67568

Ensembl

ENSG00000179010

ENSMUSG00000055302

UniProt

Q9Y605

Q9CQL7

RefSeq (mRNA)

NM_033296
NM_001272053
NM_001272054

NM_026242

RefSeq (protein)

NP_001258982
NP_001258983
NP_150638

NP_080518

Location (UCSC)Chr 4: 6.64 – 6.64 MbChr 5: 36.79 – 36.8 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

MRFAP1 has been shown to interact with MORF4L1[7][8] and Retinoblastoma protein.[7][8]

gollark: Can't believe LyricLy hasn't make macron yet.
gollark: ++remind 5h30m fix potatOS thing - validate signatures ONLY on update, try profiler or something
gollark: Yellow, due to apioform density.
gollark: Great. Do so.
gollark: I said don't use TCL. It is a bad programming language.

References

  1. GRCh38: Ensembl release 89: ENSG00000179010 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000055302 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Tominaga K, Magee DM, Matzuk MM, Pereira-Smith OM (Oct 2004). "PAM14, a novel MRG- and Rb-associated protein, is not required for development and T-cell function in mice". Molecular and Cellular Biology. 24 (19): 8366–73. doi:10.1128/MCB.24.19.8366-8373.2004. PMC 516751. PMID 15367658.
  6. "Entrez Gene: MRFAP1 Mof4 family associated protein 1".
  7. Leung JK, Berube N, Venable S, Ahmed S, Timchenko N, Pereira-Smith OM (Oct 2001). "MRG15 activates the B-myb promoter through formation of a nuclear complex with the retinoblastoma protein and the novel protein PAM14". The Journal of Biological Chemistry. 276 (42): 39171–8. doi:10.1074/jbc.M103435200. PMID 11500496.
  8. Pardo PS, Leung JK, Lucchesi JC, Pereira-Smith OM (Dec 2002). "MRG15, a novel chromodomain protein, is present in two distinct multiprotein complexes involved in transcriptional activation". The Journal of Biological Chemistry. 277 (52): 50860–6. doi:10.1074/jbc.M203839200. PMID 12397079.

Further reading


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