MAATS1

AMY-1-associating protein expressed in testis 1 is a protein that in humans is encoded by the MAATS1 (formerly known as C3orf15) gene.[5][6][7]

CFAP91
Identifiers
Aliases	CFAP91, AAT1, AAT1alpha, C3orf15, CaM-IP2, SPATA26, MYCBP associated and testis expressed 1, MAATS1, cilia and flagella associated protein 91
External IDs	OMIM: 609910 MGI: 2443598 HomoloGene: 33470 GeneCards: CFAP91
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3q13.33 Start 119,703,022 bp[1] End 119,767,102 bp[1]
Gene location (Mouse) Chr. Chromosome 16 (mouse)[2] Band 16|16 B3 Start 38,297,754 bp[2] End 38,342,143 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001948 protein binding Cellular component • cytoplasm • mitochondrion • radial spoke stalk • GO:0035085 axoneme • motile cilium • cytoskeleton • cell projection Biological process • cilium movement Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	89876	320214
Ensembl	ENSG00000183833	ENSMUSG00000022805
UniProt	Q7Z4T9	Q8BRC6
RefSeq (mRNA)	NM_033364 NM_001320316 NM_001320317 NM_001320318	NM_001081025 NM_177104
RefSeq (protein)	NP_001307245 NP_001307246 NP_001307247 NP_203528	NP_001074494
Location (UCSC)	Chr 3: 119.7 – 119.77 Mb	Chr 16: 38.3 – 38.34 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Interactions

C3orf15 has been shown to interact with MYCBP[5] and AKAP1.[5]

References

1. GRCh38: Ensembl release 89: ENSG00000183833 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000022805 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Yukitake H, Furusawa M, Taira T, Iguchi-Ariga SM, Ariga H (Nov 2002). "AAT-1, a novel testis-specific AMY-1-binding protein, forms a quaternary complex with AMY-1, A-kinase anchor protein 84, and a regulatory subunit of cAMP-dependent protein kinase and is phosphorylated by its kinase". J Biol Chem. 277 (47): 45480–92. doi:10.1074/jbc.M206201200. PMID 12223483.
6. Hayes VM, Gardiner-Garden M (Oct 2003). "Are polymorphic markers within the alpha-1-antitrypsin gene associated with risk of human immunodeficiency virus disease?". J Infect Dis. 188 (8): 1205–8. doi:10.1086/378641. PMID 14551891.
7. "Entrez Gene: C3orf15 chromosome 3 open reading frame 15".

External links

• Human MAATS1 genome location and MAATS1 gene details page in the UCSC Genome Browser.

Further reading

• Matsuda E, Ishizaki R, Taira T, et al. (2005). "Structure and characterization of AAT-1 isoforms" (PDF). Biol. Pharm. Bull. 28 (5): 898–901. doi:10.1248/bpb.28.898. PMID 15863901.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Talmud PJ, Martin S, Steiner G, et al. (2004). "Progression of atherosclerosis is associated with variation in the alpha1-antitrypsin gene". Arterioscler. Thromb. Vasc. Biol. 23 (4): 644–9. doi:10.1161/01.ATV.0000065196.61663.8D. PMID 12692006.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Mashiba S, Wada Y, Takeya M, et al. (2001). "In vivo complex formation of oxidized alpha(1)-antitrypsin and LDL". Arterioscler. Thromb. Vasc. Biol. 21 (11): 1801–8. doi:10.1161/hq1101.098232. PMID 11701469.
• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.