Clotrimazole/betamethasone dipropionate

Clotrimazole/betamethasone dipropionate, sold under the brand name Lotrisone among others, is a topical medication for the treatment of fungal infections of the feet, groin, and body in people 17 years of age and older.[1] It is a combination of clotrimazole and betamethasone dipropionate.[1] It is applied to the skin.[1]

Clotrimazole/betamethasone dipropionate
Combination of
ClotrimazoleAzole antifungal
Betamethasone dipropionateCorticosteroid
Clinical data
Trade namesLotrisone
AHFS/Drugs.comProfessional Drug Facts
License data
Routes of
administration		Topical
ATC code
Legal status
Legal status
Identifiers
UNII
KEGG

Common side effects include paresthesia, rash, edema, and secondary infections.[1]

In 2017, it was the 300th most commonly prescribed medication in the United States, with more than one million prescriptions.[2][3]

Medical uses

Clotrimazole/betamethasone dipropionate is indicated for the topical treatment of symptomatic inflammatory tinea pedis, tinea cruris, and tinea corporis due to Epidermophyton floccosum, Trichophyton mentagrophytes, and Trichophyton rubrum in people 17 years of age and older.[1]

History

Clotrimazole/betamethasone dipropionate cream was approved for use in the United States in July 1984,[4] and the lotion was approved for use in the United States in December 2000.[5]

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References
  1. "Lotrisone- clotrimazole and betamethasone dipropionate cream". DailyMed. 14 June 2019. Retrieved 13 April 2020.
  2. "The Top 300 of 2020". ClinCalc. Retrieved 11 April 2020.
  3. "Betamethasone Dipropionate; Clotrimazole - Drug Usage Statistics". ClinCalc. 23 December 2019. Retrieved 11 April 2020.
  4. "Lotrisone: FDA-Approved Drugs". U.S. Food and Drug Administration (FDA). Retrieved 13 April 2020.
  5. "Drug Approval Package: Lotrisone (Clotrizazole & Betamethasone Dipropionate) NDA #020010". U.S. Food and Drug Administration (FDA). 8 September 2004. Retrieved 13 April 2020.


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