Lipolysis-stimulated lipoprotein receptor

Lipolysis-stimulated lipoprotein receptor is a protein that in humans is encoded by the LSR gene.[5][6]

LSR
Identifiers
Aliases	LSR, ILDR3, LISCH7, lipolysis stimulated lipoprotein receptor
External IDs	OMIM: 616582 MGI: 1927471 HomoloGene: 9306 GeneCards: LSR
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19q13.12 Start 35,248,330 bp[1] End 35,267,964 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 B1 Start 30,957,770 bp[2] End 30,973,464 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001948 protein binding Cellular component • chylomicron • integral component of membrane • extracellular exosome • membrane • low-density lipoprotein particle • very-low-density lipoprotein particle • tricellular tight junction • cell membrane Biological process • regulation of lipid metabolic process • liver development • establishment of blood-brain barrier • tricellular tight junction assembly • protein localization to tricellular tight junction Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	51599	54135
Ensembl	ENSG00000105699	ENSMUSG00000001247
UniProt	Q86X29	Q99KG5
RefSeq (mRNA)	NM_001260489 NM_001260490 NM_015925 NM_205834 NM_205835	NM_001164184 NM_001164185 NM_017405
RefSeq (protein)	NP_001247418 NP_001247419 NP_057009 NP_991403 NP_991404	NP_001157656 NP_001157657 NP_059101
Location (UCSC)	Chr 19: 35.25 – 35.27 Mb	Chr 7: 30.96 – 30.97 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000105699 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000001247 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Yen FT, Masson M, Clossais-Besnard N, Andre P, Grosset JM, Bougueleret L, Dumas JB, Guerassimenko O, Bihain BE (Jun 1999). "Molecular cloning of a lipolysis-stimulated remnant receptor expressed in the liver". J Biol Chem. 274 (19): 13390–8. doi:10.1074/jbc.274.19.13390. PMID 10224102.
6. "Entrez Gene: LSR lipolysis stimulated lipoprotein receptor".

Further reading

• García JM, Peña C, García V, et al. (2008). "Prognostic value of LISCH7 mRNA in plasma and tumor of colon cancer patients". Clin. Cancer Res. 13 (21): 6351–8. doi:10.1158/1078-0432.CCR-07-0882. PMID 17975147.
• Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
• Kim JE, Tannenbaum SR, White FM (2005). "Global phosphoproteome of HT-29 human colon adenocarcinoma cells". J. Proteome Res. 4 (4): 1339–46. doi:10.1021/pr050048h. PMID 16083285.
• Benzinger A, Muster N, Koch HB, et al. (2005). "Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer". Mol. Cell. Proteomics. 4 (6): 785–95. doi:10.1074/mcp.M500021-MCP200. PMID 15778465.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Jin J, Smith FD, Stark C, et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization". Curr. Biol. 14 (16): 1436–50. doi:10.1016/j.cub.2004.07.051. PMID 15324660.
• Grimwood J, Gordon LA, Olsen A, et al. (2004). "The DNA sequence and biology of human chromosome 19". Nature. 428 (6982): 529–35. doi:10.1038/nature02399. PMID 15057824.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.