Lesinurad/allopurinol

Lesinurad/allopurinol (trade name Duzallo) is a fixed-dose combination drug for the treatment of gout. It contains 200 mg of lesinurad and 300 mg of allopurinol. In August 2017, the US Food and Drug Administration approved it for the treatment of hyperuricemia associated with gout in patients for whom target serum uric acid levels have not been achieved with allopurinol alone.[1] In February 2019, it was discontinued by its manufacturer for business reasons and is no longer available.[2]

Lesinurad/allopurinol
Combination of
Lesinuradurate transporter inhibitor
Allopurinolxanthine oxidase inhibitor
Clinical data
Trade namesDuzallo
AHFS/Drugs.comduzallo
Routes of
administration
By mouth
ATC code
Legal status
Legal status
Identifiers
KEGG

References

  1. "FDA Clears First Fixed-Dose Combination Treatment for Gout". Medscape. August 21, 2017.
  2. "DUZALLO and ZURAMPIC". Ironwood Pharmaceuticals. Retrieved 31 July 2020.
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