LRCH4

Leucine-rich repeat and calponin homology domain-containing protein 4 is a protein that in humans is encoded by the LRCH4 gene.[5][6]

LRCH4
Identifiers
AliasesLRCH4, LRN, LRRN1, LRRN4, PP14183, leucine-rich repeats and calponin homology (CH) domain containing 4, leucine rich repeats and calponin homology domain containing 4
External IDsMGI: 1917193 HomoloGene: 20532 GeneCards: LRCH4
Gene location (Human)
Chr.Chromosome 7 (human)[1]
Band7q22.1Start100,574,011 bp[1]
End100,586,129 bp[1]
RNA expression pattern




More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

4034

231798

Ensembl

ENSG00000077454

ENSMUSG00000093445

UniProt

O75427

Q921G6

RefSeq (mRNA)

NM_002319
NM_001289934

NM_001168652
NM_146164

RefSeq (protein)

NP_001276863
NP_002310

NP_001162123
NP_666276

Location (UCSC)Chr 7: 100.57 – 100.59 MbChr 5: 137.63 – 137.64 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene encodes a protein that contains leucine-rich repeats (LRR) at its amino terminus and that is known to be involved in ligand binding. The carboxyl terminus may act as a membrane anchor. Identified structural elements suggest that the encoded protein resembles a receptor.[6]

References

  1. GRCh38: Ensembl release 89: ENSG00000077454 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000093445 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Glockner G, Scherer S, Schattevoy R, Boright A, Weber J, Tsui LC, Rosenthal A (Dec 1998). "Large-Scale Sequencing of Two Regions in Human Chromosome 7q22: Analysis of 650 kb of Genomic Sequence around the EPO and CUTL1 Loci Reveals 17 Genes". Genome Res. 8 (10): 1060–73. doi:10.1101/gr.8.10.1060. PMC 310788. PMID 9799793.
  6. "Entrez Gene: LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4".

Further reading


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