LIMCH1

LIM and calponin homology domains-containing protein 1 is a protein that in humans is encoded by the LIMCH1 gene.[5][6]

LIMCH1
Identifiers
Aliases	LIMCH1, LIMCH1A, LMO7B, LIM and calponin homology domains 1
External IDs	OMIM: 617750 MGI: 1924819 HomoloGene: 18953 GeneCards: LIMCH1
Gene location (Human) Chr. Chromosome 4 (human)[1] Band 4p13 Start 41,359,607 bp[1] End 41,700,044 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 C3.1 Start 66,745,827 bp[2] End 67,057,158 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • actin binding • metal ion binding • myosin II head/neck binding Cellular component • stress fiber • myosin II complex • cytoplasm • cytoskeleton Biological process • actomyosin structure organization • positive regulation of protein phosphorylation • negative regulation of cell migration • positive regulation of stress fiber assembly • regulation of focal adhesion assembly Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	22998	77569
Ensembl	ENSG00000064042	ENSMUSG00000037736
UniProt	Q9UPQ0	Q3UH68
RefSeq (mRNA)	NM_001112717 NM_001112718 NM_001112719 NM_001112720 NM_001289122 NM_001289124 NM_014988 NM_001330672 NM_001330674 NM_001330784 NM_001330786 NM_001330787 NM_001330788 NM_001330789 NM_001330790 NM_001330791 NM_001330792 NM_001330793 NM_001330982 NM_001330983	NM_001001980 NM_001256122 NM_001368863
RefSeq (protein)	NP_001106188 NP_001106189 NP_001106190 NP_001106191 NP_001276051 NP_001276053 NP_001317601 NP_001317603 NP_001317713 NP_001317715 NP_001317716 NP_001317717 NP_001317718 NP_001317719 NP_001317720 NP_001317721 NP_001317722 NP_001317911 NP_001317912 NP_055803	NP_001001980 NP_001243051 NP_001355792
Location (UCSC)	Chr 4: 41.36 – 41.7 Mb	Chr 5: 66.75 – 67.06 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000064042 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000037736 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Kikuno R, Nagase T, Ishikawa K, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Oct 1999). "Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (3): 197–205. doi:10.1093/dnares/6.3.197. PMID 10470851.
6. "Entrez Gene: DKFZP686A01247 hypothetical protein".

Further reading

• "Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. 1999. doi:10.1101/gr.8.11.1097. PMID 9847074.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.