LCORL
Ligand dependent nuclear receptor corepressor like is a protein that in humans is encoded by the LCORL gene. [5]
Function
This gene encodes a transcription factor that appears to function in spermatogenesis. Polymorphisms in this gene are associated with measures of skeletal frame size and adult height. Alternative splicing results in multiple transcript variants.
gollark: I like Factorio, but that's more of a 3rd person shooter.
gollark: Also lasers in some mods.
gollark: That would be if the Warhammer universe wasn't an utter hellpit.
gollark: I have a laptop with highly advanced Intel HD Graphics® 620.
gollark: I've built (in creative mode) this really overengineered Botania mana generator. It makes TNT from water, cobblestone and horrendous amounts of RF (from a fusion reactor downstairs), and explodes a block of it every 0.6 seconds, which makes the entropinnyums (hidden behind that cable) produce mana.
References
- GRCh38: Ensembl release 89: ENSG00000178177 - Ensembl, May 2017
- GRCm38: Ensembl release 89: ENSMUSG00000015882 - Ensembl, May 2017
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Entrez Gene: Ligand dependent nuclear receptor corepressor like". Retrieved 2016-11-11.
Further reading
- Kunieda T, Park JM, Takeuchi H, Kubo T (2003). "Identification and characterization of Mlr1,2: two mouse homologues of Mblk-1, a transcription factor from the honeybee brain(1)". FEBS Lett. 535 (1–3): 61–5. doi:10.1016/s0014-5793(02)03858-9. PMID 12560079.
- Sovio U, Bennett AJ, Millwood IY, Molitor J, O'Reilly PF, Timpson NJ, Kaakinen M, Laitinen J, Haukka J, Pillas D, Tzoulaki I, Molitor J, Hoggart C, Coin LJ, Whittaker J, Pouta A, Hartikainen AL, Freimer NB, Widen E, Peltonen L, Elliott P, McCarthy MI, Jarvelin MR (2009). "Genetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern Finland birth cohort 1966". PLoS Genet. 5 (3): e1000409. doi:10.1371/journal.pgen.1000409. PMC 2646138. PMID 19266077.
- Soranzo N, Rivadeneira F, Chinappen-Horsley U, Malkina I, Richards JB, Hammond N, Stolk L, Nica A, Inouye M, Hofman A, Stephens J, Wheeler E, Arp P, Gwilliam R, Jhamai PM, Potter S, Chaney A, Ghori MJ, Ravindrarajah R, Ermakov S, Estrada K, Pols HA, Williams FM, McArdle WL, van Meurs JB, Loos RJ, Dermitzakis ET, Ahmadi KR, Hart DJ, Ouwehand WH, Wareham NJ, Barroso I, Sandhu MS, Strachan DP, Livshits G, Spector TD, Uitterlinden AG, Deloukas P (2009). "Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size". PLoS Genet. 5 (4): e1000445. doi:10.1371/journal.pgen.1000445. PMC 2661236. PMID 19343178.
- Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614.
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