Klaus-Peter Lesch

Klaus-Peter Lesch is a German clinical psychiatrist who has been investigating the neurobiological foundation of personality traits.

Klaus-Peter Lesch 2014

[1] His 1996 paper[2] on the association between the 5-HTTLPR polymorphism in the serotonin transporter gene and the personality trait neuroticism has been highly cited and was one of the first papers in personality genetics.

He is professor at the University of Würzburg. Among his coauthors has been Peter Riederer.

Important Publications
  • Lesch KP, Bengel D, Heils A, Sabol SZ, Greenberg BD, Petri S, Benjamin J, Müller CR, Hamer DH, Murphy DL (1996). "Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region". Science. 274 (5292): 1527–1532. doi:10.1126/science.274.5292.1527. PMID 8929413.
  • Canli T, Lesch KP (2007). "Long story short: the serotonin transporter in emotion regulation and social cognition". Nature Neuroscience. 10 (9): 1103–1109. doi:10.1038/nn1964. PMID 17726476.
  • Murphy DL, Lesch KP (2008). "Targeting the murine serotonin transporter: insights into human neurobiology". Nat Rev Neurosci. 9 (2): 85–96. doi:10.1038/nrn2284. PMID 18209729.
  • Lesch KP, Selch S, Renner TJ, Jacob C, Nguyen TT, Hahn T, Romanos M, Shoichet S, Dempfle A, Heine M, Boreatti-Hümmer A, Walitza S, Romanos J, Gross-Lesch S, Zerlaut H, Allolio B, Heinzel S, Fassnacht M, Fallgatter A, Wultsch T, Schäfer H, Warnke A, Reif A, Ropers HH, Ullmann R (2011). "Genome-wide copy number variation analysis in ADHD: association with neuropeptide Y gene dosage in an extended pedigree" (PDF). Mol Psychiatry. 16: 491–503. doi:10.1038/mp.2010.29.
  • Lesch KP, Waider J (2012). "Serotonin in the modulation of neural plasticity and networks: implications for neurodevelopmental disorders". Neuron. 76: 175–191. doi:10.1016/j.neuron.2012.09.013.
gollark: ```Architecture: x86_64CPU op-mode(s): 32-bit, 64-bitByte Order: Little EndianCPU(s): 4On-line CPU(s) list: 0-3Thread(s) per core: 1Core(s) per socket: 4Socket(s): 1NUMA node(s): 1Vendor ID: AuthenticAMDCPU family: 23Model: 1Model name: AMD Ryzen 3 1200 Quad-Core ProcessorStepping: 1CPU MHz: 3338.023CPU max MHz: 3500.0000CPU min MHz: 1550.0000BogoMIPS: 6989.03Virtualization: AMD-VL1d cache: 32KL1i cache: 64KL2 cache: 512KL3 cache: 4096KNUMA node0 CPU(s): 0-3Flags: fpu vme de pse tsc msr pae mce cx8 apic sep mtrr pge mca cmov pat pse36 clflush mmx fxsr sse sse2 ht syscall nx mmxext fxsr_opt pdpe1gb rdtscp lm constant_tsc rep_good nopl nonstop_tsc cpuid extd_apicid aperfmperf pni pclmulqdq monitor ssse3 fma cx16 sse4_1 sse4_2 movbe popcnt aes xsave avx f16c rdrand lahf_lm cmp_legacy svm extapic cr8_legacy abm sse4a misalignsse 3dnowprefetch osvw skinit wdt tce topoext perfctr_core perfctr_nb bpext perfctr_llc mwaitx cpb hw_pstate sme ssbd sev vmmcall fsgsbase bmi1 avx2 smep bmi2 rdseed adx smap clflushopt sha_ni xsaveopt xsavec xgetbv1 xsaves clzero irperf xsaveerptr arat npt lbrv svm_lock nrip_save tsc_scale vmcb_clean flushbyasid decodeassists pausefilter pfthreshold avic v_vmsave_vmload vgif overflow_recov succor smca```What clear, useful output.
gollark: `lscpu` on Li'nux.
gollark: How do you know?
gollark: https://www.dell.com/downloads/global/products/pedge/en/2950_specs.pdf
gollark: Probably 2 dual-core processors, according to this.

References
  1. "Interview with Prof. Dr. K.P. Lesch". in-cites.
  2. Klaus-Peter Lesch, D. Bengel, A. Heils, S. Z. Sabol, B. D. Greenberg, S. Petri, J. Benjamin, C. R. Muller, D. H. Hamer & D. L. Murphy (November 1996). "Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region". Science. 274 (5292): 1527–31. doi:10.1126/science.274.5292.1527. PMID 8929413.CS1 maint: multiple names: authors list (link)
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.