Klaus-Peter Lesch

Klaus-Peter Lesch is a German clinical psychiatrist who has been investigating the neurobiological foundation of personality traits.

Klaus-Peter Lesch 2014

[1] His 1996 paper[2] on the association between the 5-HTTLPR polymorphism in the serotonin transporter gene and the personality trait neuroticism has been highly cited and was one of the first papers in personality genetics.

He is professor at the University of Würzburg. Among his coauthors has been Peter Riederer.

Important Publications

  • Lesch KP, Bengel D, Heils A, Sabol SZ, Greenberg BD, Petri S, Benjamin J, Müller CR, Hamer DH, Murphy DL (1996). "Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region". Science. 274 (5292): 1527–1532. doi:10.1126/science.274.5292.1527. PMID 8929413.
  • Canli T, Lesch KP (2007). "Long story short: the serotonin transporter in emotion regulation and social cognition". Nature Neuroscience. 10 (9): 1103–1109. doi:10.1038/nn1964. PMID 17726476.
  • Murphy DL, Lesch KP (2008). "Targeting the murine serotonin transporter: insights into human neurobiology". Nat Rev Neurosci. 9 (2): 85–96. doi:10.1038/nrn2284. PMID 18209729.
  • Lesch KP, Selch S, Renner TJ, Jacob C, Nguyen TT, Hahn T, Romanos M, Shoichet S, Dempfle A, Heine M, Boreatti-Hümmer A, Walitza S, Romanos J, Gross-Lesch S, Zerlaut H, Allolio B, Heinzel S, Fassnacht M, Fallgatter A, Wultsch T, Schäfer H, Warnke A, Reif A, Ropers HH, Ullmann R (2011). "Genome-wide copy number variation analysis in ADHD: association with neuropeptide Y gene dosage in an extended pedigree" (PDF). Mol Psychiatry. 16: 491–503. doi:10.1038/mp.2010.29.
  • Lesch KP, Waider J (2012). "Serotonin in the modulation of neural plasticity and networks: implications for neurodevelopmental disorders". Neuron. 76: 175–191. doi:10.1016/j.neuron.2012.09.013.
gollark: So it is in fact sensitive data you don't want other people having access to?
gollark: And hopefully not get the results biased based on who decided to throw the most money at Google.
gollark: Then you can duckduckgo "domain registrar".
gollark: They could target them based on non-persistent contextual information like duckduckgo does, which might actually produce good suggestions without being invasive.
gollark: No, they tend to just be "here is something you already bought. Please buy it again."

References

  1. "Interview with Prof. Dr. K.P. Lesch". in-cites.
  2. Klaus-Peter Lesch, D. Bengel, A. Heils, S. Z. Sabol, B. D. Greenberg, S. Petri, J. Benjamin, C. R. Muller, D. H. Hamer & D. L. Murphy (November 1996). "Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region". Science. 274 (5292): 1527–31. doi:10.1126/science.274.5292.1527. PMID 8929413.CS1 maint: multiple names: authors list (link)
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