Klaas de Groot

Klaas de Groot (born 3 November 1940, Bergen, Limburg)[2][3] is Emeritus Professor at the Tissue Engineering Group at the University of Twente.[1] In the past he also worked as a visiting scientist at the UCLA bone research laboratory. His work has focused on the research and development of bioceramics that resemble the composition of bone. He has developed two types of bioceramic, namely bulk ceramics (dense, porous, large and small) for mechanically unloaded bone fillers, and coatings for improving the bone bonding of strong, but less biocompatible, metallic orthopedic and dental implants. His group also studied the incorporation of drugs and growth factors such as Bone Morphogenetic Proteins (BMP)[4] into such ceramics and coatings,[5] as well as the use of calciumphosphate particles for plastic surgery, i.e. filling and augmenting soft and hard tissues for cosmetic reasons[6]).

For the Dutch Olympic wrestler, see Klaas de Groot (wrestler).
Klaas de Groot
Klaas de Groot
Nationality The Netherlands
AwardsChinese Friendship award;

The Clemson award (USA); The George Winter award (EU); The Somiya Award (2003);

The John Charnley Award (by the USA Hip Society);[1] The Gold Medal by Acta Biomaterialia
Scientific career
FieldsBiomedical Engineering, Biomaterials, Tissue Engineering
InstitutionsUniversity of Twente

CAM Implants

His research products are being marketed by CAM Implants (now Cam Bioceramics), IsoTis and Stryker (USA).

Prior to his present appointment he worked at Vrije Universiteit (VU), Amsterdam (until 1988) and Leiden University (until 2001), at both places as head of the department of biomaterials.[1]

He is a co-founder of CAM Implants BV (now Cam Bioceramics), and IsoTis. He has published more than 350 articles and he is the co-inventor of about 10 patents.[1]

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References
  1. Klaas de Groot faculty profile at University of Twente
  2. Acta Biomaterialia Gold Medal 2016 awarded to Klaas de Groot
  3. Klaas de Groot at Leiden faculty since 1575 website
  4. De Groot, J (1998). "Carriers that concentrate native bone morphogenetic protein in vivo". Tissue Eng. 4 (4): 337–41. doi:10.1089/ten.1998.4.337. PMID 9916166.
  5. Liu, Y; Y Liu, K de Groot, E B Hunziker (May 2005). "BMP-2 liberated from biomimetic implant coatings induces and sustains direct ossification in an ectopic rat model". Bone. 36 (5): 745–57. doi:10.1016/j.bone.2005.02.005. ISSN 8756-3282. PMID 15814303.CS1 maint: multiple names: authors list (link)
  6. P Habibovic, C M van der Valk, C A van Blitterswijk, K De Groot, G Meijer. "Influence of octacalcium phosphate coating on osteoinductive properties of biomaterials". Journal of Materials Science: Materials in Medicine. 2004/04 (15(4)): 373–80. ISSN 0957-4530. PMID 15332602.CS1 maint: multiple names: authors list (link)


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