KBTBD10

Kelch repeat and BTB domain-containing protein 10 is a protein that in humans is encoded by the KBTBD10 gene.[5][6]

KLHL41
Identifiers
Aliases	KLHL41, KBTBD10, Krp1, NEM9, SARCOSIN, kelch like family member 41
External IDs	OMIM: 607701 MGI: 2683854 HomoloGene: 4421 GeneCards: KLHL41
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2q31.1 Start 169,509,702 bp[1] End 169,526,258 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 C2 Start 69,670,120 bp[2] End 69,684,230 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • ubiquitin-protein transferase activity • GO:0001948 protein binding Cellular component • cytoplasm • M band • cell projection • pseudopodia • endoplasmic reticulum membrane • membrane • ruffle • Cul3-RING ubiquitin ligase complex • cell membrane • sarcoplasmic reticulum • endoplasmic reticulum • sarcoplasmic reticulum membrane • cytoskeleton • cell nucleus • cytosol Biological process • regulation of skeletal muscle cell differentiation • regulation of lateral pseudopodium assembly • myofibril assembly • regulation of myoblast differentiation • protein ubiquitination • skeletal muscle cell differentiation • striated muscle contraction • regulation of myoblast proliferation • sarcomere organization • skeletal muscle fiber development • post-translational modification Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	10324	228003
Ensembl	ENSG00000239474	ENSMUSG00000075307
UniProt	O60662	A2AUC9
RefSeq (mRNA)	NM_006063	NM_001081087
RefSeq (protein)	NP_006054	NP_001074556
Location (UCSC)	Chr 2: 169.51 – 169.53 Mb	Chr 2: 69.67 – 69.68 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000239474 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000075307 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Taylor A, Obholz K, Linden G, Sadiev S, Klaus S, Carlson KD (Apr 1999). "DNA sequence and muscle-specific expression of human sarcosin transcripts". Mol Cell Biochem. 183 (1–2): 105–12. doi:10.1023/A:1006824331819. PMID 9655184.
6. "Entrez Gene: KBTBD10 kelch repeat and BTB (POZ) domain containing 10".

Further reading

• Foster LJ, Rudich A, Talior I, et al. (2006). "Insulin-dependent interactions of proteins with GLUT4 revealed through stable isotope labeling by amino acids in cell culture (SILAC)". J. Proteome Res. 5 (1): 64–75. doi:10.1021/pr0502626. PMID 16396496.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Lim DS, Roberts R, Marian AJ (2001). "Expression Profiling of Cardiac Genes in Human Hypertrophic Cardiomyopathy: Insight Into the Pathogenesis of Phenotypes". J. Am. Coll. Cardiol. 38 (4): 1175–80. doi:10.1016/S0735-1097(01)01509-1. PMC 2776821. PMID 11583900.
• Spence HJ, Johnston I, Ewart K, et al. (2000). "Krp1, a novel kelch related protein that is involved in pseudopod elongation in transformed cells". Oncogene. 19 (10): 1266–76. doi:10.1038/sj.onc.1203433. PMID 10713668.
• Hillier LD, Lennon G, Becker M, et al. (1997). "Generation and analysis of 280,000 human expressed sequence tags". Genome Res. 6 (9): 807–28. doi:10.1101/gr.6.9.807. PMID 8889549.

External links

• KBTBD10 human gene location in the UCSC Genome Browser.
• KBTBD10 human gene details in the UCSC Genome Browser.